Fluorescence-based optical fiber sensor for liquid sample analysis in silica glass well
Liquid samples are often of interest for various analytical purposes, requiring rapid, precise, portable, and easy-to-use equipment. Then, we proposed a portable system for fluorescence spectroscopy was developed, integrating an optical fiber sensor into a single-well plate. A proof-of-concept of the system was demonstrated using two different fluorescence samples: chlorophyll and cyanobacteria culture. The manufacturing method employed was ultrafast laser-assisted etching (ULAE), and the optical fiber was custom-mounted for tip-endcap integration. The fluorescence analysis demonstrated an enhancement in the signal of the liquid sample through the integration of the fiber capture system in the detector.
Authors
- José Francisco Algorri (ORCID: https://orcid.org/0000-0002-2654-583X)
- Maria Gabriela Fernández-Manteca
- Luis Rodŕıguez-Cobo (ORCID: https://orcid.org/0000-0002-2068-2956)
- Adolfo Cobo (ORCID: https://orcid.org/0000-0003-1498-9238)
- José Miguel López Higuera (ORCID: https://orcid.org/0000-0002-8615-8487)
- Celia Gómez-Galdós
- Andrea Perez-Asensio
- Borja García-García
Institutions
- Universidad de Cantabria (ES)
- Instituto de Salud Carlos III (ES)
- Instituto de Investigación Marqués de Valdecilla (ES)
Publication Details
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1117/12.3062257
- Primary Topic
- Advanced Fiber Optic Sensors
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina
- Instituto de Investigación Marqués de Valdecilla
- Instituto de Salud Carlos III
- European Regional Development Fund
- Agencia Estatal de Investigación