Eyelid Pilomatrixomas: A Case Report and Comprehensive Literature Review

Pilomatrixomas are rare, benign tumors of the hair follicle that can be found all over the body and, rarely, the eyelid. Despite their benign nature, pilomatrixomas can be misdiagnosed due to their similarity to other eyelid conditions. Diagnosis can be challenging and requires a combination of clinical skills, imaging studies, and histopathology. As a result, a comprehensive understanding of their presentation and management strategies is essential for healthcare providers. Herein, the unusual case of a 13-year-old female patient with a rapidly progressive eyelid pilomatrixoma is presented. A comprehensive review of the current literature regarding eyelid pilomatrixomas was performed. This literature review aims to synthesize existing research and case studies related to pilomatrixomas of the eyelid, focusing on their etiology, differential diagnosis, treatment options, and potential complications.

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Publication Details

Journal
Cureus
Published
2025-05-22
DOI
https://doi.org/10.7759/cureus.84639
Primary Topic
Cancer and Skin Lesions
Type
article
Field-Weighted Citation Impact
0.00
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article

Eyelid Pilomatrixomas: A Case Report and Comprehensive Literature Review

Katie Topping, Kim D. Thompson, Gesa Schäfer
Cureus
Cancer and Skin Lesions
article

Eyelid Pilomatrixomas: A Case Report and Comprehensive Literature Review

Katie Topping, Kim D. Thompson, Gesa Schäfer
article en

Abstract

Pilomatrixomas are rare, benign tumors of the hair follicle that can be found all over the body and, rarely, the eyelid. Despite their benign nature, pilomatrixomas can be misdiagnosed due to their similarity to other eyelid conditions. Diagnosis can be challenging and requires a combination of clinical skills, imaging studies, and histopathology. As a result, a comprehensive understanding of their presentation and management strategies is essential for healthcare providers. Herein, the unusual case of a 13-year-old female patient with a rapidly progressive eyelid pilomatrixoma is presented. A comprehensive review of the current literature regarding eyelid pilomatrixomas was performed. This literature review aims to synthesize existing research and case studies related to pilomatrixomas of the eyelid, focusing on their etiology, differential diagnosis, treatment options, and potential complications.

CureusVol. 17(5)
Loma Linda University Medical Center (US), Loma Linda University (US), The University of Texas Southwestern Medical Center (US)
Openalex Percentile: Top 79%
Cancer and Skin Lesions
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