Detecting early cardiomyopathy in transthyretin variant carriers: reappraising the diagnostic value of Perugini grade 1 radiotracer uptake on bone scintigraphy
Our findings suggest that Perugini grade 1 cardiac radiotracer uptake is an early marker of ATTR-CM in TTRv carriers, potentially enabling earlier diagnosis and intervention.
Authors
- Riemer H. J. A. Slart (ORCID: https://orcid.org/0000-0002-5565-1164)
- Friso L. H. Muntinghe
- Hans Nienhuis (ORCID: https://orcid.org/0000-0003-3974-6830)
- Bouke P. C. Hazenberg (ORCID: https://orcid.org/0000-0003-1827-0482)
- Christoph Kimmich
- J. Bijzet
- M Berends
- Paul A. van der Zwaag (ORCID: https://orcid.org/0000-0001-6693-0321)
- Ewout J. Houwerzijl
- Alwin Tubben (ORCID: https://orcid.org/0000-0001-8414-958X)
- Christian Knackstedt (ORCID: https://orcid.org/0000-0002-5457-3010)
- Hendrea S. A. Tingen (ORCID: https://orcid.org/0000-0002-8572-9428)
- Peter van der Meer (ORCID: https://orcid.org/0000-0002-9705-4413)
Institutions
- University Medical Center Groningen (NL)
- Maastricht University (NL)
- Klinikum Oldenburg (DE)
- University of Twente (NL)
Publication Details
- Journal
- European Journal of Nuclear Medicine and Molecular Imaging
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1007/s00259-025-07328-6
- Citations
- 1
- Primary Topic
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 0.81