Staphylococcus aureus detection based on tapered MCF
A new tapered multicore fiber (MCF) biosensor is proposed and implemented for <i>Staphylococcus aureus</i> detection based on analyte/aptamer specific binding assay. The tapered MCF was functionalized with a specific aptamer for selective detection. In experiments, the selectivity was tested by comparing <i>S. aureus</i> and <i>S. epidermidis</i> detection using tapered MCF, and the sensitivity was evaluated by detecting different concentrations of <i>S. aureus</i> at 10<sup>5</sup>, 10<sup>6</sup>, and 10<sup>7</sup> CFU/mL. The results represent the tapered MCF's successful application as a fiber optic biosensor.
Authors
- María Ángeles Tormo‐Más (ORCID: https://orcid.org/0000-0001-8928-2697)
- David Barrera (ORCID: https://orcid.org/0000-0002-1700-6842)
- Valeria Hernández-Ambato (ORCID: https://orcid.org/0000-0002-0988-6990)
- Elena Aznar (ORCID: https://orcid.org/0000-0003-0361-3876)
- Salvador Sales (ORCID: https://orcid.org/0000-0001-9457-976X)
- Ramón Martínez‐Máñez (ORCID: https://orcid.org/0000-0001-5873-9674)
Institutions
- Biomedical Research Networking Center in Bioengineering, Biomaterials and Nanomedicine (ES)
- Instituto de Investigación Sanitaria La Fe (ES)
- Universitat Politècnica de València (ES)
Publication Details
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1117/12.3062936
- Primary Topic
- Image Processing Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00