PPARα deficiency exacerbates retinal pathological changes and dysfunction in high-fat diet mice
In HFD-fed mice retina, particularly in the inner retina, <i>PPARα</i> knockout increases lipid metabolic abnormalities, inflammatory responses, oxidative stress, apoptosis initiation and dysfunction.
Authors
- Zhengxuan Jiang (ORCID: https://orcid.org/0000-0001-7620-8658)
- Chaofeng Yu
- Li‐Ming Tao (ORCID: https://orcid.org/0000-0001-9258-0441)
- Dandan Xiao (ORCID: https://orcid.org/0000-0003-3278-6717)
- Xue Wang (ORCID: https://orcid.org/0009-0006-7955-4410)
Institutions
- Central South University (CN)
- Anhui Medical University (CN)
- Suzhou University of Science and Technology (CN)
- Second Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- International Journal of Ophthalmology
- Published
- 2025-05-23
- DOI
- https://doi.org/10.18240/ijo.2025.06.03
- Primary Topic
- Peroxisome Proliferator-Activated Receptors
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Anhui Medical University