Brain Characteristics in Patients With Myelin Oligodendrocyte Glycoprotein Antibody‐Associated Disorder by 7.0 Tesla <scp>MRI</scp>
In our observational MOGAD cohort, all three types of cortical lesions were recognized, with intracortical lesions being the most common. The number and proportion of lesions with MVS were higher than those with CVS. Lesions with paramagnetic phase changes were rare and non-rim-like in appearance. These findings provide a better understanding of the underlying pathology of MOGAD and will help in the differentiation of MOGAD from other demyelinating disorders.
Authors
- Yunyun Duan
- Huabing Wang (ORCID: https://orcid.org/0000-0002-6848-2590)
- Claudia Chien (ORCID: https://orcid.org/0000-0001-8280-9513)
- Lei Su (ORCID: https://orcid.org/0000-0002-5569-1991)
- Xiaoyu Shi (ORCID: https://orcid.org/0009-0009-4955-5836)
- Friedemann Paul (ORCID: https://orcid.org/0000-0002-6378-0070)
- Yaou Liu (ORCID: https://orcid.org/0000-0003-4352-5774)
- Joseph Kuchling (ORCID: https://orcid.org/0000-0002-7981-2073)
- Carsten Finke (ORCID: https://orcid.org/0000-0002-7665-1171)
- Mengting Zhang
- Thoralf Niendorf (ORCID: https://orcid.org/0000-0001-7584-6527)
- De‐Cai Tian (ORCID: https://orcid.org/0000-0002-5153-2491)
- Yujing Li (ORCID: https://orcid.org/0000-0002-3223-769X)
- Michael Levy (ORCID: https://orcid.org/0000-0002-7969-8346)
- Jing Jing (ORCID: https://orcid.org/0000-0001-9822-5758)
- Fu‐Dong Shi (ORCID: https://orcid.org/0000-0002-9675-4637)
- Zhe Zhang (ORCID: https://orcid.org/0009-0006-8199-7456)
- Chenyang Gao (ORCID: https://orcid.org/0000-0003-2390-0792)
- Xinyao Liu (ORCID: https://orcid.org/0009-0007-0478-8981)
- Ai Guo (ORCID: https://orcid.org/0000-0003-2658-0106)
Institutions
- Harvard University (US)
- Capital Medical University (CN)
- Max Delbrück Center (DE)
- Tianjin Medical University General Hospital (CN)
- Beijing Tian Tan Hospital (CN)
- Massachusetts General Hospital (US)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Annals of Clinical and Translational Neurology
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1002/acn3.70080
- Citations
- 1
- Primary Topic
- Multiple Sclerosis Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- National Natural Science Foundation of China