ADSCs attenuate Liver fibrosis via inducing HSC senescence: validation in dual-etiology models
Our findings indicate that ADSCs transplantation can mitigate fibrosis by inducing the senescence of aHSCs and reducing collagen production.
Authors
- Hui Liu (ORCID: https://orcid.org/0000-0003-4027-499X)
- Renyong Lin (ORCID: https://orcid.org/0000-0001-6210-4719)
- Tuerganaili Aji (ORCID: https://orcid.org/0000-0001-6737-8874)
- Jin Chu (ORCID: https://orcid.org/0000-0003-4606-6585)
- Xiaojuan Bi (ORCID: https://orcid.org/0000-0002-8287-1138)
- Junlong Xue
- Nuerbaiti Kusuman
- Xue Zhang (ORCID: https://orcid.org/0000-0002-8179-138X)
- Li Liang (ORCID: https://orcid.org/0000-0003-0991-7360)
- Xiaolong He (ORCID: https://orcid.org/0000-0002-4599-6599)
- Ning Yang (ORCID: https://orcid.org/0000-0002-7457-6307)
- Guodong Lü (ORCID: https://orcid.org/0009-0004-8833-5071)
- Mukexina Mulati
Institutions
- Xinjiang Medical University (CN)
- First Affiliated Hospital of Xinjiang Medical University (CN)
Publication Details
- Journal
- PLoS neglected tropical diseases
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1371/journal.pntd.0013094
- Citations
- 4
- Primary Topic
- Liver physiology and pathology
- Type
- article
- Field-Weighted Citation Impact
- 5.29
Funders
- Natural Science Foundation of Xinjiang Province
- National Natural Science Foundation of China
- Natural Science Foundation of Xinjiang