Exploring the association between mild behavioral impairment and plasma p‐tau217: Implications for early detection of Alzheimer's disease
Mild behavioral impairment (MBI) is linked to elevated plasma p-tau217, a specific Alzheimer's disease biomarker.MBI increases the odds of plasma p-tau217 positivity in dementia-free individuals.Findings support MBI as an early indicator for Alzheimer's disease risk.MBI assessment can improve biomarker-based screening and clinical trial efficiency.
Authors
- Zahinoor Ismail (ORCID: https://orcid.org/0000-0002-5529-3731)
- Eric Edward Smith (ORCID: https://orcid.org/0000-0003-3956-1668)
- Maryam Ghahremani (ORCID: https://orcid.org/0000-0001-8063-713X)
- Rebeca Leon
Institutions
- University of Calgary (CA)
Publication Details
- Journal
- Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring
- Published
- 2025-04-01
- DOI
- https://doi.org/10.1002/dad2.70119
- Citations
- 6
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 8.83
Funders
- U.S. Department of Defense
- Alzheimer's Disease Neuroimaging Initiative
- National Institute for Health and Care Research
- Canadian Institutes of Health Research
- National Institute on Aging
- National Institute of Biomedical Imaging and Bioengineering