A high-saturated, long-chain fatty acid ketogenic diet negatively impacts visual and motor-sensory function in a pre-clinical model of multiple sclerosis
We propose that the anti-inflammatory neuroprotective benefits of a KD are limited when saturated, long-chain fatty acids are used, and that chain length and fat saturation should be taken into account when utilizing KD as a treatment.
Authors
- Benjamin W. Elwood (ORCID: https://orcid.org/0000-0002-5289-0645)
- Randy H. Kardon (ORCID: https://orcid.org/0000-0002-3173-7123)
- Oliver W. Gramlich (ORCID: https://orcid.org/0000-0001-6948-0522)
- Jeffrey J. Anders
- Erin N Capper
Institutions
- University of Iowa (US)
- University of Alabama at Birmingham (US)
- Iowa City VA Health Care System (US)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-05-22
- DOI
- https://doi.org/10.3389/fimmu.2025.1587760
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- U.S. Department of Veterans Affairs
- Rehabilitation Research and Development Service