Functional connectivity in distributed cortical networks associated with semantic processing in healthy older adults
Despite trends of decreased functional specialization in aging, and prior evidence within this cohort of broad task-related activation and connectivity bilaterally, semantic task relevance remained uniquely localized to left hemisphere semantic network hubs. Increased coherence within DAN and DMN during rhyme blocks may reflect novelty of the rhyming task, underscoring flexible network recruitment for demanding tasks in healthy aging. Findings contribute to our understanding of underlying neural mechanisms involved in semantic processing in cognitive aging.
Authors
- Kailey Langer (ORCID: https://orcid.org/0000-0002-1588-1635)
- Ronald A. Cohen (ORCID: https://orcid.org/0000-0002-8863-8847)
- Adam J. Woods (ORCID: https://orcid.org/0000-0002-0786-0236)
- Eric C. Porges (ORCID: https://orcid.org/0000-0003-3885-5859)
- Alexa Chen (ORCID: https://orcid.org/0000-0002-9180-8712)
- Alexandria O’Neal
- John B. Williamson (ORCID: https://orcid.org/0000-0001-9456-1797)
- Amanda Garcia
Institutions
- University of Florida Health (US)
- University of Florida (US)
- James A. Haley Veterans' Hospital (US)
- Florida Atlantic University (US)
Publication Details
- Journal
- Frontiers in Aging Neuroscience
- Published
- 2025-05-22
- DOI
- https://doi.org/10.3389/fnagi.2025.1479861
- Citations
- 1
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.43
Funders
- Brain Research Foundation
- McKnight Foundation
- Evelyn F. McKnight Brain Research Foundation