Gut microbiota dysbiosis and metabolic shifts in pediatric norovirus infection: a metagenomic study in Northeast China
Our findings reveal novel associations between NoV infection and gut microbiota dysbiosis, particularly the enrichment of <i>Bacteroides uniformis</i>, which may influence host-pathogen interactions via metabolic or immune mechanisms. The identified microbial and metabolic signatures offer potential biomarkers for diagnosis and targets for microbiota-based therapeutic strategies in pediatric NoV infection.
Authors
- Xinhong Wei (ORCID: https://orcid.org/0000-0003-2647-6595)
- Lizhen Piao (ORCID: https://orcid.org/0009-0008-4754-3922)
- Xiaofei Zhang (ORCID: https://orcid.org/0000-0003-4516-9179)
- Z.-X. Wang
- Hong Wang (ORCID: https://orcid.org/0000-0001-9136-8959)
Institutions
- Jilin University (CN)
- Shandong Provincial Hospital (CN)
- Shandong First Medical University (CN)
- Union Hospital (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-05-22
- DOI
- https://doi.org/10.3389/fcimb.2025.1600470
- Primary Topic
- Viral gastroenteritis research and epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00