Distinct effects of global signal regression on brain activity during propofol and sevoflurane anesthesia
These findings reveal that GSR's impact on functional brain organization is anesthetic-specific, with sevoflurane-induced changes being particularly sensitive to global signal removal. Our results suggest that GSR should be applied cautiously when comparing different anesthetic agents and highlight the importance of considering drug-specific effects when analyzing consciousness-related brain activity.
Authors
- Ho‐Ching Yang (ORCID: https://orcid.org/0000-0003-2670-1772)
- Xuanling Chen (ORCID: https://orcid.org/0000-0002-4969-7465)
- Zhenhu Liang (ORCID: https://orcid.org/0000-0002-2467-9877)
- Lunxu Li
- Lan Yao (ORCID: https://orcid.org/0000-0003-4356-6672)
- Juan Wang (ORCID: https://orcid.org/0000-0002-1596-2179)
- Xiaoli Li (ORCID: https://orcid.org/0000-0003-1359-5130)
- Fa Lu
Institutions
- Peking University (CN)
- Beijing Normal University (CN)
- Yanshan University (CN)
- Chinese Institute for Brain Research (CN)
- Peking University International Hospital (CN)
- Indiana University School of Medicine
- Indiana University – Purdue University Indianapolis (US)
Publication Details
- Journal
- Frontiers in Neuroscience
- Published
- 2025-05-22
- DOI
- https://doi.org/10.3389/fnins.2025.1576535
- Primary Topic
- Anesthesia and Sedative Agents
- Type
- article
- Field-Weighted Citation Impact
- 0.00