Shared genetics and causal relationship between sociability and the brain’s default mode network

By combining genomic and transcriptomic data, our gene prioritization strategy may serve as a blueprint for future studies. Our findings can guide further research into the biological mechanisms underlying sociability and its role in the development, prognosis, and treatment of neuropsychiatric disorders.

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Publication Details

Journal
Psychological Medicine
Published
2025-01-01
DOI
https://doi.org/10.1017/s0033291725000832
Primary Topic
Functional Brain Connectivity Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Shared genetics and causal relationship between sociability and the brain’s default mode network

Martina Arenella, Alessandro Serretti, Emma Sprooten, Jamie Robinson et al.
Psychological Medicine
Functional Brain Connectivity Studies
article

Shared genetics and causal relationship between sociability and the brain’s default mode network

Martina Arenella, Alessandro Serretti, Emma Sprooten, Jamie Robinson, Nina Roth Mota, Giuseppe Fanelli, Barbara Franke, Martien J. Kas, Till F. M. Andlauer, Janita Bralten, Chiara Fabbri, Maroš Rovný
article en

Abstract

By combining genomic and transcriptomic data, our gene prioritization strategy may serve as a blueprint for future studies. Our findings can guide further research into the biological mechanisms underlying sociability and its role in the development, prognosis, and treatment of neuropsychiatric disorders.

Psychological MedicineVol. 55
Boehringer Ingelheim (Germany) (DE), Radboud University Nijmegen (NL), University of Groningen (NL), King's College London (GB), MRC Cognition and Brain Sciences Unit (GB), University of Cambridge (GB), Università degli Studi di Enna Kore (IT), TUM Klinikum (DE), Radboud University Medical Center (NL), Oasi Maria SS (IT), Istituti di Ricovero e Cura a Carattere Scientifico (IT), Technical University of Munich (DE), University of Bologna (IT)
European Federation of Pharmaceutical Industries and Associations, European Commission, National Institutes of Health, Horizon 2020 Framework Programme, National Institute of Mental Health
Openalex Percentile: Top 89%
Functional Brain Connectivity Studies
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Shared genetics and causal relationship between sociability and the brain’s default mode network — Martina Arenella, Alessandro Serretti, et al. · Psychological Medicine (2025) | TGRS Research Map | TGRS