Heat delivery accompanying pulsed field ablation

Pulsed Field Ablation (PFA) is a technique to achieve pulmonary vein isolation, alternative to the traditional thermal ablation procedures. Instead of delivering or subtracting heat, PFA uses rapid pulses of a high intensity electric field, inducing cells electroporation. PFA is usually claimed not to influence the temperature in the surroundings of the ablation site. Nevertheless, in some case a non-negligible increase of the patient's luminal esophageal temperature has been observed. Here we set up a mathematical model to provide a theoretical basis to the latter observation, considering a worst case scenario.

Authors

Institutions

Publication Details

Journal
Journal of Theoretical Biology
Published
2025-05-22
DOI
https://doi.org/10.1016/j.jtbi.2025.112145
Citations
3
Primary Topic
Combustion and Detonation Processes
Type
article
Field-Weighted Citation Impact
14.98
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Heat delivery accompanying pulsed field ablation

Massimo Grimaldi, Fabio Rosso, Antonio Fasano, Angiolo Farína
3 citations
Journal of Theoretical Biology
Combustion and Detonation Processes
14.98
article

Heat delivery accompanying pulsed field ablation

Massimo Grimaldi, Fabio Rosso, Antonio Fasano, Angiolo Farína
article en
3 citations

Abstract

Pulsed Field Ablation (PFA) is a technique to achieve pulmonary vein isolation, alternative to the traditional thermal ablation procedures. Instead of delivering or subtracting heat, PFA uses rapid pulses of a high intensity electric field, inducing cells electroporation. PFA is usually claimed not to influence the temperature in the surroundings of the ablation site. Nevertheless, in some case a non-negligible increase of the patient's luminal esophageal temperature has been observed. Here we set up a mathematical model to provide a theoretical basis to the latter observation, considering a worst case scenario.

Journal of Theoretical BiologyVol. 610
Ospedale Generale Regionale Francesco Miulli (IT), Flint Institute Of Arts (US), University of Florence (IT), University of Bari Aldo Moro (IT)
Affordable and clean energy
Openalex Percentile: Top 2%
Combustion and Detonation Processes
14.98
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Heat delivery accompanying pulsed field ablation — Massimo Grimaldi, Fabio Rosso, et al. · Journal of Theoretical Biology (2025) | TGRS Research Map | TGRS