Heat delivery accompanying pulsed field ablation
Pulsed Field Ablation (PFA) is a technique to achieve pulmonary vein isolation, alternative to the traditional thermal ablation procedures. Instead of delivering or subtracting heat, PFA uses rapid pulses of a high intensity electric field, inducing cells electroporation. PFA is usually claimed not to influence the temperature in the surroundings of the ablation site. Nevertheless, in some case a non-negligible increase of the patient's luminal esophageal temperature has been observed. Here we set up a mathematical model to provide a theoretical basis to the latter observation, considering a worst case scenario.
Authors
- Massimo Grimaldi (ORCID: https://orcid.org/0000-0002-9347-8884)
- Fabio Rosso (ORCID: https://orcid.org/0000-0002-3631-4314)
- Antonio Fasano (ORCID: https://orcid.org/0000-0003-4116-5496)
- Angiolo Farína (ORCID: https://orcid.org/0000-0001-5558-3723)
Institutions
- Ospedale Generale Regionale Francesco Miulli (IT)
- Flint Institute Of Arts (US)
- University of Florence (IT)
- University of Bari Aldo Moro (IT)
Publication Details
- Journal
- Journal of Theoretical Biology
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1016/j.jtbi.2025.112145
- Citations
- 3
- Primary Topic
- Combustion and Detonation Processes
- Type
- article
- Field-Weighted Citation Impact
- 14.98