Population-based longitudinal study over two decades of Candida and Candida-like species bloodstream infection reveals gender and species differences in mortality, recurrence and resistance
Our study highlights important shifts in causative species and resistance patterns of Ca-BSI which impacts clinical management. Antifungal resistance rates were low overall. The identification of new modifiable and non-modifiable risk factors for recurrence and mortality provides opportunities to examine new strategies to improve patient outcomes.
Authors
- Kevin B. Laupland (ORCID: https://orcid.org/0000-0002-1205-5354)
- Sharon C.-A. Chen
- Adam G. Stewart (ORCID: https://orcid.org/0000-0002-7262-7529)
- Monica A. Slavin (ORCID: https://orcid.org/0000-0002-8443-314X)
- Sarah P. Hammond (ORCID: https://orcid.org/0000-0002-4271-7443)
- Sophia Koo (ORCID: https://orcid.org/0000-0002-4973-7439)
- Patrick N. A. Harris (ORCID: https://orcid.org/0000-0002-2895-0345)
- David Paterson (ORCID: https://orcid.org/0000-0003-0409-9012)
- Felicity Edwards (ORCID: https://orcid.org/0000-0002-9896-841X)
Institutions
- Brigham and Women's Hospital (US)
- Royal Brisbane and Women's Hospital (AU)
- Peter MacCallum Cancer Centre (AU)
- Westmead Hospital (AU)
- Massachusetts General Hospital (US)
- Dana-Farber Cancer Institute (US)
Publication Details
- Journal
- Journal of Infection
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1016/j.jinf.2025.106513
- Citations
- 7
- Primary Topic
- Antifungal resistance and susceptibility
- Type
- article
- Field-Weighted Citation Impact
- 9.77
Funders
- Queensland Health