<sup> <i>n</i> </sup> Bu <sub>4</sub> NBr-catalyzed esterification of methoxyarenes with acyl bromide

The catalytic esterification of methoxyarenes remains challenging, especially for C(sp<sup>3</sup>)-O bond functionalization. Herein, we report a simple and efficient method using <sup><i>n</i></sup>Bu<sub>4</sub>NBr as a catalyst to directly convert methoxyarenes and acyl bromides into esters under solvent-free conditions. This strategy provides a simple and efficient approach, achieving yields of up to 95%.

Authors

Jiang‐Fei Li
Ting Sun (ORCID: https://orcid.org/0000-0002-3647-7703)
Qin Zhu (ORCID: https://orcid.org/0000-0002-9307-1603)
Guodong Wang (ORCID: https://orcid.org/0000-0002-6262-7453)
Wenchao Zhu (ORCID: https://orcid.org/0009-0001-2639-6643)
Shaoyin Wang (ORCID: https://orcid.org/0000-0003-2576-566X)

Institutions

Wannan Medical College (CN)

Publication Details

Journal: Organic & Biomolecular Chemistry
Published: 2025-01-01
DOI: https://doi.org/10.1039/d5ob00612k
Primary Topic: Catalytic Cross-Coupling Reactions
Type: article
Field-Weighted Citation Impact: 0.00

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article

ⁿ Bu ₄ NBr-catalyzed esterification of methoxyarenes with acyl bromide

Jiang‐Fei Li, Ting Sun, Qin Zhu, Guodong Wang et al.

Jan 1, 2025

Organic & Biomolecular Chemistry

Catalytic Cross-Coupling Reactions

article

ⁿ Bu ₄ NBr-catalyzed esterification of methoxyarenes with acyl bromide

Jiang‐Fei Li, Ting Sun, Qin Zhu, Guodong Wang, Wenchao Zhu, Shaoyin Wang

January 1, 2025article en

Abstract

The catalytic esterification of methoxyarenes remains challenging, especially for C(sp<sup>3</sup>)-O bond functionalization. Herein, we report a simple and efficient method using <sup><i>n</i></sup>Bu<sub>4</sub>NBr as a catalyst to directly convert methoxyarenes and acyl bromides into esters under solvent-free conditions. This strategy provides a simple and efficient approach, achieving yields of up to 95%.

Organic & Biomolecular ChemistryVol. 23(24)

Wannan Medical College (CN)

Openalex Percentile: Top 91%

Catalytic Cross-Coupling Reactions

DOI Source OpenAlex

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