Rationally designed anti-autophagy nanosystems for reversing the immunosuppressive network in the tumor environment
The CQCP system synergistically reverses PDAC immunosuppression by restoring antigen presentation and activating innate immunity. This dual-targeted strategy demonstrates robust antitumor efficacy and offers a promising immunotherapy approach for PDAC.
Authors
- Jing-Yun Su (ORCID: https://orcid.org/0000-0003-3499-0244)
- Bo‐Dou Zhang
- Shao‐Hua Zhuo
- Jun Wu (ORCID: https://orcid.org/0000-0001-6113-8976)
- Yufen Zhao (ORCID: https://orcid.org/0000-0003-3560-435X)
- Lang Zhao (ORCID: https://orcid.org/0009-0000-4052-7526)
- Xi Chen (ORCID: https://orcid.org/0000-0001-5661-515X)
- Ling Liu (ORCID: https://orcid.org/0000-0002-7041-2508)
- Wenhao Li (ORCID: https://orcid.org/0000-0003-0817-8500)
- Yanmei Li (ORCID: https://orcid.org/0000-0003-1215-5010)
- Tianyang Wang (ORCID: https://orcid.org/0000-0002-7256-883X)
- Tao Yang (ORCID: https://orcid.org/0000-0001-8944-8028)
- Li-Jun Yang
Institutions
- Ningbo University (CN)
- Shanxi Medical University (CN)
- Peking University (CN)
- Chinese Institute for Brain Research (CN)
- First Hospital of Shanxi Medical University (CN)
- Peking University First Hospital (CN)
- Tsinghua University (CN)
Publication Details
- Journal
- Nanomedicine
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1080/17435889.2025.2508133
- Citations
- 1
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 0.67
Funders
- Tsinghua University