Inflammatory crosstalk: systemic gut-kidney interplay aggravates tumor host mortality
Paraneoplastic syndromes affect multiple organs and are a central cause of mortality in cancer patients. In this issue, Cong et al (2025) report an inflammatory gut-kidney axis mediating systemic complications in Drosophila hosts with neoplastic tumors. These results suggest novel potential therapeutic targets in cancer patients.
Authors
- Héctor Herranz (ORCID: https://orcid.org/0000-0001-5808-1593)
Institutions
- University of Copenhagen (DK)
Publication Details
- Journal
- The EMBO Journal
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1038/s44318-025-00457-6
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00