RISK PROFILE OF THROMBOTIC DISEASE IN PATIENTS WITH COVID

Objective: Determine the profile of patients with Cardiovascular Risk Factors with COVID who, after being discharged from the hospital, developed Acute Myocardial Infarction (AMI) or Venous Thromboembolic Disease (VTE) in the first 12 weeks.Design and method: Among the risk factors for cardiovascular disease, the following were considered: High blood pressure, diabetes mellitus, dyslipidemia, chronic obstructive pulmonary disease (COPD), smoking, age, sex, chronic kidney disease (CKD). It is a retrospective, observational study in which we reviewed 155 Clinical records of patients who were admitted to the hospital for SARS COV2, of which 21 were eliminated due to lack of data. Of the remaining 134 patients, we reviewed whether during the following 12 weeks after discharge they had suffered an acute myocardial infarction or any venous thromboembolic disease (Pulmonary thromboembolism or deep vein thrombosis). Patients over 18 years of age were included, the mean age was 66.66 years (±16.81), the 56% (75) were men. Patients who had suffered AMI or VTE prior to or during admission or were pregnant were excluded. Results: The most frequent cardiovascular risk factor was Hypertension with 51.5%(69), followed by dyslipidemia 38.8% (52), diabetes mellitus 26.9% (36). Less frequent were: Atrial fibrillation 11.9% (16), COPD 11.9% (16) and CKD 10.4% (14). The 7.5% (10) of the patients had AMI and 2.2% (3) VTE. This group was 80.3 (±10.3) years older than the group that did not suffer from these diseases, which was 65.6 (±16.8) years old, this difference being statistically significant t= 2.73 p= 0.007. It was observed that there is a statistically significant relationship between AMI and Hypertension, p = .001, AMI and DL, p = .047, AMI and atrial fibrillation, p = .019. There were no statistically significant differences between the other risk factors included. Conclusions: The presence of Hypertension, dyslipidemia, atrial fibrillation and age were the most important risk factors in patients with COVID for developing AMI after hospital discharge.