The ameliorative role of phlorotannin on aflatoxin B1-induced liver oxidative stress and mitochondrial injury is related to the activation of Nrf2 and Nrf1 signaling pathways in broilers
The PT ameliorates oxidative stress and hepatotoxicity by activating the Nrf2-mediated phase II detoxification enzymes pathway and maintains mitochondrial homeostasis by activating the Nrf1 signaling pathway in broilers exposed to AFB<sub>1</sub>.
Authors
- Qinghua Yao (ORCID: https://orcid.org/0000-0002-0302-4433)
- Balamuralikrishnan Balasubramanian (ORCID: https://orcid.org/0000-0001-6938-1495)
- Xue-Qing Ye
- Yuying Yang (ORCID: https://orcid.org/0009-0002-4331-1418)
- Mengyi Huang (ORCID: https://orcid.org/0000-0002-9224-5907)
- Rajesh Jha (ORCID: https://orcid.org/0000-0002-2891-8353)
- Wen‐Chao Liu
Institutions
- University of Hawaiʻi at Mānoa (US)
- Sejong University (KR)
- Guangdong Ocean University (CN)
Publication Details
- Journal
- Journal of Animal Science and Biotechnology/Journal of animal science and biotechnology
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1186/s40104-025-01210-z
- Citations
- 8
- Primary Topic
- Genomics, phytochemicals, and oxidative stress
- Type
- article
- Field-Weighted Citation Impact
- 6.45