HISTOPATHOLOGICAL STUDY OF UPPER GASTROINTESTINAL ENDOSCOPIC BIOPSIES

Introduction: According to National cancer registry, esophageal and gastric cancers are the most common cancer in men and in women esophageal cancer is third most common cancer after carcinoma of breast and cervix[4,5] Early detection of malignancy greatly improves the survival rate of the patients. Endoscopy followed by histopathological evaluation is the gold standard for diagnosis (7). This study was done to determine the histopathologic spectrum of Upper Gastrointestinal Tract Mucosal Biopsies. A cross-sec Materials And Methods: tional study of upper GI endoscopic biopsy was carried out in Bharati Vidyapeeth (Deemed to Be University) Medical College and Hospital, Sangli. After obtaining ethical clearance (reference number: BV(DU)/MCH/2398/19-20), a total of 50 cases were identied of endoscopic biopsies over the period of 18 months from November 2019 to April 2021. After proper processing and H&E staining, tumors were diagnosed as per WHO histological classication of gastrointestinal tumors and lymphoproliferative disorders. Out of 50 U Results: GIE biopsies, 37 (74%) were non neoplastic lesions whereas neoplastic lesions were 13 (26%) only. Esophageal biopsies 13, gastric biopsies 27 and duodenal biopsies 10. Majority of cases were non neoplastic and male predominance was seen in all neoplastic lesions. Conclusion: There is good correlation between both the endoscopic and histopathological diagnosis. Endoscopy gives us the exact site of the lesion from which endoscopic guided biopsy can be taken followed by the gold standard method which is histopathological examination.