Feline Cryptococcosis due to <i>Cryptococcus gattii</i> VGII (Recently Renamed as <i>C. deuterogattii</i> ) in an FIV‐Positive Cat With Demodicosis From Manaus, Central Amazon, Brazil
This case report documents the diagnosis and successful treatment of cryptococcosis caused by <i>Cryptococcus gattii</i> VGII in a 20-month-old male domestic shorthair cat from Manaus, Brazil, which was concurrently infected with feline immunodeficiency virus (FIV) and diagnosed with demodicosis. The cat presented with mucopurulent nasal discharge, cutaneous lesions on the neck, and a subcutaneous mass between the shoulder blades. Laboratory investigations, including fine-needle aspiration cytology, fungal culture, and PCR-RFLP genotyping, confirmed the presence of <i>C. gattii</i> VGII. The cat was treated with fluconazole (10 mg/kg/day) and topical fluralaner-moxidectin, resulting in complete clinical resolution of all lesions and associated symptoms. This report underscores the significance of considering cryptococcosis as a differential diagnosis in immunocompromised cats presenting with cutaneous or respiratory symptoms. Additionally, it highlights the importance of recognizing the Amazon region as an area of environmental prevalence of <i>C. gattii</i> VGII, reinforcing the need for awareness regarding its impact on animal health.
Authors
- Ana Cláudia Alves Cortez (ORCID: https://orcid.org/0000-0002-0425-8661)
- Naira Sulany Oliveira de Sousa (ORCID: https://orcid.org/0000-0002-9344-1192)
- Sara Letícia dos Santos Andrade (ORCID: https://orcid.org/0000-0001-6174-2698)
- Kátia Santana Cruz (ORCID: https://orcid.org/0000-0002-3295-7937)
- João Vicente Braga de Souza (ORCID: https://orcid.org/0000-0002-3163-7499)
- Ormezinda Celeste Cristo Fernandes (ORCID: https://orcid.org/0000-0001-5752-5017)
- Jacqueline da Silva Batista (ORCID: https://orcid.org/0000-0002-6649-6200)
- Hagen Frickmann (ORCID: https://orcid.org/0000-0002-8967-9528)
- Ani Beatriz Jackisch‐Matsuura (ORCID: https://orcid.org/0000-0001-5686-1828)
- Eveleise Samira Martins Canto (ORCID: https://orcid.org/0000-0002-3439-6643)
- Érica Simplício de Souza (ORCID: https://orcid.org/0000-0002-2389-4401)
- Flávia da Silva Fernandes (ORCID: https://orcid.org/0000-0003-1591-7025)
- Adriana Oliveira da Silva Queiroz (ORCID: https://orcid.org/0009-0003-7542-0448)
- João Fernando Vieira Ennes (ORCID: https://orcid.org/0009-0002-0721-3976)
- Nayara de Fátima Lazameth-Diniz (ORCID: https://orcid.org/0000-0003-0394-6101)
Institutions
- Universidade Federal do Oeste do Pará (BR)
- Instituto Nacional de Pesquisas da Amazônia (BR)
- Fundação de Medicina Tropical (BR)
- Bundeswehrkrankenhaus (DE)
- Institute of Medical Microbiology and Hygiene (DE)
- Escola Superior de Ciências da Saúde (BR)
- Universidade do Estado do Amazonas (BR)
Publication Details
- Journal
- Case Reports in Veterinary Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1155/crve/8368783
- Primary Topic
- Fungal Infections and Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universidade Federal do Amazonas
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Fundação de Amparo à Pesquisa do Estado do Amazonas