Explaining Uncertain Hepatoprotective Effects: When Silibinin Co-Administered with Other Drugs
The results of the cell experiment showed that silibinin's liver protective effects were uncertain when it was combined with CBZ. FAERS database analysis revealed elevated risks of ADRs with silibinin co-administration, collectively highlighting the necessity for vigilance against unanticipated herb-drug interactions.
Authors
- Ji Li (ORCID: https://orcid.org/0000-0002-2931-798X)
- Feng Yu (ORCID: https://orcid.org/0000-0002-7021-8588)
- Pu Dong (ORCID: https://orcid.org/0000-0001-9729-5869)
- Qinwei Sun (ORCID: https://orcid.org/0009-0006-2824-6100)
- Sisi Wang (ORCID: https://orcid.org/0009-0005-4911-8792)
- Zengxiang Zhao (ORCID: https://orcid.org/0000-0001-9113-3922)
Institutions
- China Pharmaceutical University (CN)
Publication Details
- Journal
- Medeniyet Medical Journal
- Published
- 2025-05-22
- DOI
- https://doi.org/10.4274/mmj.galenos.2025.71163
- Primary Topic
- Silymarin and Mushroom Poisoning
- Type
- article
- Field-Weighted Citation Impact
- 0.00