METTL16 accelerates lung adenocarcinoma progression by inducing N6-methyladenosine modification of GTSE1 to regulate p53 pathway and cell cycle
These results indicate that METTL16-mediated m<sup>6</sup>A modification of GTSE1 accelerates LUAD progression by regulating p53 pathway and cell cycle. The aforementioned findings suggest METTL16 and GTSE1 may serve as potential targets for LUAD management.
Authors
- Fang Liu (ORCID: https://orcid.org/0000-0003-3456-160X)
- Sheng Jin (ORCID: https://orcid.org/0000-0001-6110-0783)
Institutions
- Jianghan University (CN)
- Wuhan University (CN)
- Wuhan No.1 Hospital (CN)
- Hubei Zhongshan Hospital (CN)
Publication Details
- Journal
- Cell Division
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1186/s13008-025-00156-y
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.00