The impact of aripiprazole on neurocognitive function in individuals at clinical high risk for psychosis: A comparison with olanzapine and non-antipsychotic treatment
These findings suggest potential associations between antipsychotic use and cognitive outcomes in CHR populations while recognizing that observed differences may reflect baseline illness severity rather than medication effects alone. Aripiprazole may offer specific advantages over olanzapine, underscoring the importance of individualized risk-benefit evaluations in treatment planning. Randomized controlled trials are needed to establish causality.
Authors
- YuQing Gao
- HaiChun Liu
- Jijun Wang (ORCID: https://orcid.org/0000-0001-5427-7425)
- JiaYi Ye
- Tao Chen (ORCID: https://orcid.org/0000-0003-2987-6711)
- HuiRu Cui (ORCID: https://orcid.org/0000-0001-5171-1871)
- XiaoChen Tang (ORCID: https://orcid.org/0000-0003-3796-7111)
- Andrea Raballo (ORCID: https://orcid.org/0000-0003-3709-4111)
- Lihua Xu (ORCID: https://orcid.org/0000-0002-2237-9336)
- Chunbo Li (ORCID: https://orcid.org/0000-0002-3387-4439)
- Liu Xiao-hua (ORCID: https://orcid.org/0000-0002-5781-5775)
- Dan Zhang
- Tianhong Zhang (ORCID: https://orcid.org/0000-0002-5379-7119)
- Yingying Tang
- YeGang Hu (ORCID: https://orcid.org/0000-0001-8742-1673)
- YanYan Wei (ORCID: https://orcid.org/0000-0002-8218-1954)
- Wenjun Su (ORCID: https://orcid.org/0000-0002-7587-8446)
- Jianzhong Zeng (ORCID: https://orcid.org/0009-0000-0369-5301)
Institutions
- University of Waterloo (CA)
- Shanghai Jiao Tong University (CN)
- Harvard University Press (US)
- Shanghai Mental Health Center (CN)
- Center for Excellence in Brain Science and Intelligence Technology (CN)
- Organizzazione Sociopsichiatrica Cantonale (CH)
- Institute of Psychology, Chinese Academy of Sciences (CN)
- Università della Svizzera italiana (CH)
- Academia Sinica (TW)
Publication Details
- Journal
- European Psychiatry
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1192/j.eurpsy.2025.2459
- Citations
- 2
- Primary Topic
- Treatment of Major Depression
- Type
- article
- Field-Weighted Citation Impact
- 2.79
Funders
- Shanghai Municipal Health Commission
- National Natural Science Foundation of China