Analysis of p53-Independent Functions of the Mdm2-MdmX Complex Using Data-Independent Acquisition-Based Profiling
We selected a potential target from the DIA analysis and validated it by immunoblotting and qPCR, and this allows us to demonstrate a new interaction partner of the Mdm2-MdmX complex in human cells.
Authors
- Karl A.T. Makepeace (ORCID: https://orcid.org/0000-0001-9584-2750)
- Lewis M. Brown (ORCID: https://orcid.org/0000-0002-1864-3077)
- Rafaela Muniz de Queiroz (ORCID: https://orcid.org/0000-0001-5962-9071)
- Jayanta K. Chakrabarty
- Carol Prives (ORCID: https://orcid.org/0000-0003-1846-5562)
- Anu Jain
Institutions
- Columbia University (US)
Publication Details
- Journal
- Proteomes
- Published
- 2025-05-22
- DOI
- https://doi.org/10.3390/proteomes13020018
- Primary Topic
- Cancer-related Molecular Pathways
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- New York State Stem Cell Science