Nasopharyngeal Carcinoma and Head and Neck Cancer in Type 2 Diabetes after SGLT2I, DPP4I, and GLP1a Use
This study provided real-world evidence that SGLT2Is were associated with lower risks of NPC but not of head and neck cancer when compared with DPP4Is among patients with T2DM. SGLT2Is should be considered before DPP4Is about the risks of NPC in regions with high prevalence of NPC.
Authors
- Oscar Hou In Chou (ORCID: https://orcid.org/0000-0001-7058-4708)
- Catherine Po Ling Chan (ORCID: https://orcid.org/0000-0003-4755-2155)
- Lifang Li (ORCID: https://orcid.org/0000-0003-4917-5701)
- Gary Tse (ORCID: https://orcid.org/0000-0001-5510-1253)
- Jiandong Zhou (ORCID: https://orcid.org/0000-0003-3780-9033)
- Tong Liu (ORCID: https://orcid.org/0000-0003-0482-0738)
- Guoliang Li (ORCID: https://orcid.org/0000-0002-2352-9404)
- Yifan Yang (ORCID: https://orcid.org/0000-0002-5106-0471)
- Cheuk To Chung (ORCID: https://orcid.org/0000-0002-0420-5359)
- Bernard Man Yung Cheung (ORCID: https://orcid.org/0000-0001-9106-7363)
- Kar Kei Mak (ORCID: https://orcid.org/0009-0002-6150-2162)
- Wing Tak Wong (ORCID: https://orcid.org/0000-0002-4514-3780)
Institutions
- Medway School of Pharmacy (GB)
- Chinese University of Hong Kong (HK)
- Shanghai Jiao Tong University (CN)
- King's College London (GB)
- Systems Analytics (United States) (US)
- Prince of Wales Hospital (CN)
- ID Genomics (United States) (US)
- First Affiliated Hospital of Xi'an Jiaotong University (CN)
- Second Hospital of Tianjin Medical University (CN)
- HKU-Pasteur Research Pole (HK)
- Metropolitan University (BD)
- Tianjin Medical University (CN)
- Xi'an Jiaotong University (CN)
- University of Hong Kong (HK)
Publication Details
- Journal
- Cancer Prevention Research
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1158/1940-6207.capr-24-0349
- Primary Topic
- Peptidase Inhibition and Analysis
- Type
- article
- Field-Weighted Citation Impact
- 0.00