Autophagy modulation by hADSCs and green light therapy alleviates inflammation and promotes functional recovery after spinal cord injury
The combined treatment of hADSCs transplantation and GL therapy significantly improves functional recovery and reduces inflammation following SCI. The therapeutic effects are mediated in part by the modulation of microglial autophagy.
Authors
- Liyi Zhou
- Hongxin Xie (ORCID: https://orcid.org/0000-0002-6268-4423)
- Daoyuan Jiang
- Hui Zhang (ORCID: https://orcid.org/0000-0001-8049-6525)
- Liang Li (ORCID: https://orcid.org/0000-0003-0745-2571)
- Huan Xie
- Bin Gu (ORCID: https://orcid.org/0000-0003-0663-7363)
- Zhilai Zhou (ORCID: https://orcid.org/0000-0001-6975-6314)
- Quanxin He
- Junjie Chen (ORCID: https://orcid.org/0000-0001-6371-3700)
Institutions
- Jinan University (CN)
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- Guangdong Provincial People's Hospital (CN)
- Southern Medical University (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Stem Cell Research & Therapy
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1186/s13287-025-04367-6
- Citations
- 3
- Primary Topic
- Spinal Cord Injury Research
- Type
- article
- Field-Weighted Citation Impact
- 4.41
Funders
- Natural Science Foundation of Guangzhou City