The Association Between Dexmedetomidine and Bradycardia: An Analysis of FDA Adverse Event Reporting System (FAERS) Data and Transcriptomic Profiles
Key clinical takeaways include the co-presentation of multiple cardiovascular ADEs, including cardiac arrest, hypotension, and syncope, alongside dexmedetomidine-associated bradycardia. Furthermore, several possible DDIs with dexmedetomidine were also identified.
Authors
- Feng Cheng (ORCID: https://orcid.org/0000-0003-3619-8090)
- Weiru Han (ORCID: https://orcid.org/0000-0002-6264-3090)
- Robert Morris (ORCID: https://orcid.org/0000-0002-6994-0602)
- X. X. Zhu (ORCID: https://orcid.org/0000-0003-0828-299X)
- Kun Bu (ORCID: https://orcid.org/0009-0006-9526-3023)
- Suguna Aishwarya Kuppa (ORCID: https://orcid.org/0009-0007-3438-9340)
Institutions
- University of South Florida (US)
Publication Details
- Journal
- Genes
- Published
- 2025-05-22
- DOI
- https://doi.org/10.3390/genes16060615
- Citations
- 4
- Primary Topic
- Anesthesia and Sedative Agents
- Type
- article
- Field-Weighted Citation Impact
- 8.76