Age-related distribution of human papillomavirus genotypes in women with cervical squamous cell carcinoma from Linyi, China, 2015–2023
Our study revealed that HPV genotype diversity in CSCC patients varies with age, highlighting the need for age-stratified and personalized cervical cancer prevention strategies. Enhanced screening efforts for older women are essential because of the greater genotypes diversity in this group. Additionally, the observed trends in HPV prevalence over time suggest that HPV vaccination has effectively reduced the incidence of CSCC in women under 45 years of age. These findings emphasize the importance of expanding vaccination coverage and optimizing screening programs to further reduce the cervical cancer burden across different age groups.
Authors
- Hanlin Zhang (ORCID: https://orcid.org/0000-0001-5065-4086)
- Guanglong Dong (ORCID: https://orcid.org/0000-0002-5545-1912)
- Yu-Xia Zhou (ORCID: https://orcid.org/0000-0002-7576-2419)
- Xiaohong Zhang (ORCID: https://orcid.org/0000-0003-2320-0884)
- Yiming Wang (ORCID: https://orcid.org/0000-0003-0513-9039)
- Zhihui Wang (ORCID: https://orcid.org/0000-0003-2234-144X)
- Mei Xue (ORCID: https://orcid.org/0000-0002-9380-0634)
- Jianxiang Geng
- Haiyan Hou (ORCID: https://orcid.org/0000-0002-3052-1259)
- Haibo Liu (ORCID: https://orcid.org/0000-0002-4213-2883)
Institutions
- Qingdao University (CN)
- Nanjing University of Chinese Medicine (CN)
- Nanchang University (CN)
- Shandong University (CN)
- Linyi People's Hospital (CN)
- Jiangsu Province Hospital (CN)
Publication Details
- Journal
- Virology Journal
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1186/s12985-025-02790-y
- Citations
- 3
- Primary Topic
- Cervical Cancer and HPV Research
- Type
- article
- Field-Weighted Citation Impact
- 4.06