A primary cell model of the very preterm epithelium reveals barrier defects at 1 year of age
The airway epithelial barrier appears compromised in survivors of very preterm birth at 1 year of age. Reduced epithelial barrier strength creates vulnerability to infection and injury, which can negatively impact overall lung health across the lifespan.
Authors
- Shannon J. Simpson (ORCID: https://orcid.org/0000-0002-4895-0975)
- Anthony Kicic (ORCID: https://orcid.org/0000-0002-0008-9733)
- Denby J. Evans (ORCID: https://orcid.org/0000-0003-0483-0880)
- Samantha A McLean (ORCID: https://orcid.org/0000-0002-0189-534X)
Institutions
- The Kids Research Institute Australia (AU)
- The University of Western Australia (AU)
- Curtin University (AU)
- Harry Perkins Institute of Medical Research (AU)
- Princess Margaret Hospital for Children (AU)
- Respiratory Clinical Trials (AU)
- Perth Children's Hospital
Publication Details
- Journal
- ERJ Open Research
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1183/23120541.00037-2025
- Primary Topic
- Neonatal Respiratory Health Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Perpetual