Lung MRI scoring reveals persistence of emphysema-like changes in lungs of infants born preterm at (pre)school age
Persisting structural changes in the BPD lung are dominated by underlying immaturity and demonstrate an emphysema-like phenotype, potentially fitting the concept of dysanapsis. Lung MRI can inform treatment and monitoring strategies through the provision of additional information on disease characteristics and severity.
Authors
- Benjamin Schubert (ORCID: https://orcid.org/0000-0003-3412-1102)
- Anne Hilgendorff (ORCID: https://orcid.org/0000-0002-3725-996X)
- Kathrin Strobl (ORCID: https://orcid.org/0009-0007-4011-7288)
- Folke Brinkmann (ORCID: https://orcid.org/0000-0002-4307-4232)
- Friederike Häfner (ORCID: https://orcid.org/0000-0003-1488-6490)
- Florian Heinen (ORCID: https://orcid.org/0000-0002-3872-6136)
- Sophia Stoecklein (ORCID: https://orcid.org/0000-0003-0325-4674)
- Kai Förster (ORCID: https://orcid.org/0000-0002-4127-1400)
- Andreas W. Flemmer (ORCID: https://orcid.org/0000-0002-4601-0314)
- Denise Steffinger
- Olaf Dietrich (ORCID: https://orcid.org/0000-0001-6182-5039)
- Alida S. D. Kindt (ORCID: https://orcid.org/0000-0001-6551-6030)
Institutions
- Leiden University (NL)
- Carl von Ossietzky Universität Oldenburg (DE)
- Helmholtz Zentrum München (DE)
- LMU Klinikum (DE)
- Universitäres Kinderwunschzentrum Lübeck (DE)
- University Hospital Schleswig-Holstein (DE)
- Zero to Three (US)
- German Center for Lung Research (DE)
- Technical University of Munich (DE)
- Ludwig-Maximilians-Universität München (DE)
- University of Lübeck (DE)
Publication Details
- Journal
- ERJ Open Research
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1183/23120541.01183-2024
- Citations
- 2
- Primary Topic
- Congenital Diaphragmatic Hernia Studies
- Type
- article
- Field-Weighted Citation Impact
- 4.01
Funders
- Bayer
- Deutsche Forschungsgemeinschaft
- Bundesministerium für Bildung und Forschung
- Albert-Ludwigs-Universität Freiburg
- Ludwig-Maximilians-Universität München
- Deutsches Zentrum für Lungenforschung
- Siemens Healthineers
- Helmholtz Zentrum München