DRUG UTILIZATION STUDY AND MORBIDITY PATTERN IN INDOOR PATIENTS AT TERTIARY CARE HOSPITAL IN HIGH RISK PREGNANCY : PREGNANCY INDUCED HYPERTENSION, OLIGOHYDRAMNIOS, INTRAUTERINE GROWTH RETARDATION & DIABETES MELLITUS.

Background: Pregnancy represents a special physiological state during which the use of drug is of growing concern due to risk of teratogenicity. High risk pregnancy is common threat to mother and foetus. Therefore, our aim was to study the drug utilization and morbidity pattern in high risk pregnancy in hospitalized pregnant women. Methods: An observational, prospective study was carried out in 150 patients for 12 months in the tertiary care hospital. Protocol was approved by the Institutional IEC (Intistutional ethics committe). The data were collected in a pre-designed proforma. Data were analysed by using Microsoft excel 2021 & Graphpad prism software 2021. Results: Among 150 patients, 5 (3.3%), 103 (68.7%) and 42 (28 %) were of less than 20, 20 to 30 and more than 30 years of age respectively. About 50.7 % women had complained of abdominal pain and 36.7 % had pedal oedema followed by headache (29.3%), weakness (12.7%) and cough ( 8 %). Folic acid (84.7 %) and ferrous sulphate (83.3 %) were the commonest drugs prescribed followed by calcium carbonate (73.3%), vitamin B complex (70.7%), labetelol (65.3%) and protein powder (44 %). As per FDA Drug Risk Category, Category-A (45.1%) was most frequently prescribed followed by Category-B (27.3%) and Category-C (26.5 %). Percentage of drugs prescribed by generic name and from essential drug list was 71.5% and 89.5%. Conclusion: Folic acid, ferrous sulphate and calcium carbonate were most commonly prescribed drugs. There is more number of drugs prescribed by generic name.