Are Osteoarthritis Inflammation and Its Related Sensorimotor Interactions Both Noteworthy and Modifiable Key Players?

Joints are sensitive structures whose qualitative and quantitative components depend not only on the harmonious interactions of hormones, enzymes, vitamins, minerals and protein, but also on the stresses put upon them by function as well as their intrinsic and extrinsic neuromotor environments, activity and integrity. This paper reviews some recent pathological insights regarding the synovial joint’s lining and its immune cellular responses that indicate when traumatized may evoke a possible unstoppable cascade of inflammation and possible cartilage destruction unless abated in a timely way. One essential movement correlate that may especially fail to limit the spread of osteoarthritis inflammation and its oftentimes severe repercussions, namely muscle dysfunction is specifically discussed. Based on what is known we argue in favor of its possible untapped utility in efforts to reverse or mitigate post traumatic arthritis, especially in the face of persistent mechanical impacts.

Authors

Publication Details

Journal
Journal of Orthopaedic Science and Research
Published
2025-05-22
DOI
https://doi.org/10.46889/josr.2025.6203
Primary Topic
Osteoarthritis Treatment and Mechanisms
Type
article
Field-Weighted Citation Impact
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article

Are Osteoarthritis Inflammation and Its Related Sensorimotor Interactions Both Noteworthy and Modifiable Key Players?

Ray Marks
Journal of Orthopaedic Science and Research
Osteoarthritis Treatment and Mechanisms
article

Are Osteoarthritis Inflammation and Its Related Sensorimotor Interactions Both Noteworthy and Modifiable Key Players?

Ray Marks
article en

Abstract

Joints are sensitive structures whose qualitative and quantitative components depend not only on the harmonious interactions of hormones, enzymes, vitamins, minerals and protein, but also on the stresses put upon them by function as well as their intrinsic and extrinsic neuromotor environments, activity and integrity. This paper reviews some recent pathological insights regarding the synovial joint’s lining and its immune cellular responses that indicate when traumatized may evoke a possible unstoppable cascade of inflammation and possible cartilage destruction unless abated in a timely way. One essential movement correlate that may especially fail to limit the spread of osteoarthritis inflammation and its oftentimes severe repercussions, namely muscle dysfunction is specifically discussed. Based on what is known we argue in favor of its possible untapped utility in efforts to reverse or mitigate post traumatic arthritis, especially in the face of persistent mechanical impacts.

Journal of Orthopaedic Science and Research
Openalex Percentile: Top 82%
Osteoarthritis Treatment and Mechanisms
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Are Osteoarthritis Inflammation and Its Related Sensorimotor Interactions Both Noteworthy and Modifiable Key Players? — Ray Marks · Journal of Orthopaedic Science and Research (2025) | TGRS Research Map | TGRS