Enhancing biomedical relation extraction through data-centric and preprocessing-robust ensemble learning approach

The paper describes our biomedical relation extraction system, which is designed to participate in the BioCreative VIII challenge Track 1: BioRED Track, which emphasizes the relation extraction from biomedical literature. Our system employs an ensemble learning method, leveraging the PubTator API in conjunction with multiple pretrained bidirectional encoder representations from transformer (BERT) models. Various preprocessing inputs are incorporated, encompassing prompt questions, entity ID pairs, and co-occurrence contexts. To enhance model comprehension, special tokens and boundary tags are incorporated. Specifically, we utilize PubMedBERT alongside the Max Rule ensemble learning mechanism to amalgamate outputs from diverse classifiers. Our findings surpass the established benchmark score, thereby providing a robust benchmark for evaluating performance in this task. Moreover, our study introduces and demonstrates the effectiveness of a data-centric approach, emphasizing the significance of prioritizing high-quality data instances in enhancing model performance and robustness.

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Database
Published
2025-01-01
DOI
https://doi.org/10.1093/database/baae127
Primary Topic
Biomedical Text Mining and Ontologies
Type
article
Field-Weighted Citation Impact
0.00

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article

Enhancing biomedical relation extraction through data-centric and preprocessing-robust ensemble learning approach

Richard Tzong‐Han Tsai, Jen-Chieh Han, Hsi-Chuan Hung, Chi-Shun Hsueh et al.
Database
Biomedical Text Mining and Ontologies
article

Enhancing biomedical relation extraction through data-centric and preprocessing-robust ensemble learning approach

Richard Tzong‐Han Tsai, Jen-Chieh Han, Hsi-Chuan Hung, Chi-Shun Hsueh, Yu Zhang, Wilailack Meesawad
article en

Abstract

The paper describes our biomedical relation extraction system, which is designed to participate in the BioCreative VIII challenge Track 1: BioRED Track, which emphasizes the relation extraction from biomedical literature. Our system employs an ensemble learning method, leveraging the PubTator API in conjunction with multiple pretrained bidirectional encoder representations from transformer (BERT) models. Various preprocessing inputs are incorporated, encompassing prompt questions, entity ID pairs, and co-occurrence contexts. To enhance model comprehension, special tokens and boundary tags are incorporated. Specifically, we utilize PubMedBERT alongside the Max Rule ensemble learning mechanism to amalgamate outputs from diverse classifiers. Our findings surpass the established benchmark score, thereby providing a robust benchmark for evaluating performance in this task. Moreover, our study introduces and demonstrates the effectiveness of a data-centric approach, emphasizing the significance of prioritizing high-quality data instances in enhancing model performance and robustness.

DatabaseVol. 2025
National Central University (TW), Cathay General Hospital (TW), Research Center for Humanities and Social Sciences, Academia Sinica (TW)
Ministry of Science and Technology, Taiwan
Openalex Percentile: Top 90%
Biomedical Text Mining and Ontologies
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