Integrating genetic polymorphisms and clinical data to develop predictive models for skin toxicity in breast cancer radiation therapy

Our findings highlight the importance of combining clinical data with genetic markers to enhance the accuracy of models predicting RT toxicity in BC.

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Publication Details

Journal
The Breast
Published
2025-05-22
DOI
https://doi.org/10.1016/j.breast.2025.104506
Primary Topic
Effects of Radiation Exposure
Type
article
Field-Weighted Citation Impact
0.00

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article

Integrating genetic polymorphisms and clinical data to develop predictive models for skin toxicity in breast cancer radiation therapy

Orland Dı́ez, Maria Carmen De Santis, Sheryl Green, Ester Aguado-Flor et al.
1 links
The Breast
Effects of Radiation Exposure
article

Integrating genetic polymorphisms and clinical data to develop predictive models for skin toxicity in breast cancer radiation therapy

Orland Dı́ez, Maria Carmen De Santis, Sheryl Green, Ester Aguado-Flor, Chris J. Talbot, Rebecca Elliott, J. Giralt, Adam Webb, Alexandra Giraldo, Tim Rattay, Manuel Altabas, Guillermo Villacampa, Ana Vega, Liv Veldeman, D. Azria, Barry S. Rosenstein, Paolo Zunino, Alison M. Dunning, Carlotta Giandini, T. Rancati, Sara Gutiérrez‐Enríquez, Adinda Baten, Maarten Lambrecht, Miguel E. Aguado‐Barrera, Meritxell Mollà, Marie-Pierre Farcy Jacquet, Caroline Weltens, Petra Seibold, C. Bourgier, Laura Duran-Lozano, Catharine West, Elena Sperk, Chris Monten, Hilary Stobart, Renée Bultijnck, Carlos Lopez-Pleguezuelos, Vı́ctor Navarro, Victoria Reyes, Jenny Chang‐Claude, R.P. Symonds, Dirk De Ruysscher
article en

Abstract

Our findings highlight the importance of combining clinical data with genetic markers to enhance the accuracy of models predicting RT toxicity in BC.

The BreastVol. 82
Hebron University (PS), University of Leicester (GB), Inserm (FR), Universität Hamburg (DE), German Cancer Research Center (DE), Université de Montpellier (FR), Heidelberg University (DE), Manchester Academic Health Science Centre (GB), Universitair Ziekenhuis Leuven (BE), Ghent University Hospital (BE), Cancer Research UK (GB), University Hospital Heidelberg (DE), University of Manchester (GB), Maastricht University (NL), Vall d'Hebron Institut de Recerca (ES), Centre Hospitalier Universitaire de Nîmes (FR), University Medical Center Hamburg-Eppendorf (DE), Fundación Pública Galega de Medicina Xenómica (ES), University Cancer Center Hamburg (DE), Vall d'Hebron Hospital Universitari (ES), The Christie NHS Foundation Trust (GB), Institut de Recherche en Cancérologie de Montpellier (FR), Instituto de Investigación Sanitaria de Santiago (ES), University Medical Centre Mannheim (DE), Fondazione IRCCS Istituto Nazionale dei Tumori (IT), Patient Advocate Foundation (US), MRC Epidemiology Unit (GB), Maastro Clinic (NL), The Patients Association (GB), Vall d'Hebron Institute of Oncology (ES), Université de Nîmes (FR), Politecnico di Milano (IT), Icahn School of Medicine at Mount Sinai (US), KU Leuven (BE)
Fundación Cellex, Deutsches Krebsforschungszentrum, Centres de Recerca de Catalunya, Cancer Research UK, National Institute for Health and Care Research, European Commission, Agence Nationale de la Recherche, Bundesministerium für Bildung und Forschung, Generalitat de Catalunya, Universitair Ziekenhuis Gent, KU Leuven, Universiteit Gent, Vedecká Grantová Agentúra MŠVVaŠ SR a SAV, Bundesamt für Strahlenschutz, Universitätsmedizin Mannheim, Fondazione Regionale per la Ricerca Biomedica, Manchester Biomedical Research Centre, Instituto de Salud Carlos III
Good health and well-being
Openalex Percentile: Top 82%
Effects of Radiation Exposure
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