Community-Acquired Pneumonia with Pseudomonas aeruginosa in a Geriatric Patient with Rheumatoid Arthritis under Baricitinib Treatment

Community-acquired pneumonia (CAP) in older patients presents unique diagnostic challenges. Unlike typical presentations with fever and cough, older adults may experience atypical symptoms like falls, confusion, or chronic disease deterioration. Immunomodulatory treatments for autoimmune diseases further complicate infection risks. This is the first case of a severe Pseudomonas aeruginosa pneumonia in an 86-year-old rheumatoid arthritis patient on baricitinib and prednisone. Initially admitted after a fall, she showed no respiratory symptoms but had a chest x-ray revealing extensive infiltrative consolidation. Sputum analysis confirmed the pneumonia, which was successfully treated with antibiotics. Following the resolution of the infection, the immunomodulatory therapy could be safely reintroduced. The case underscores the critical need for comprehensive diagnostic evaluation in older adults on immunomodulatory therapy, emphasizing that subtle, non-respiratory symptoms can mask serious infections and require heightened clinical suspicion.

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Journal
Annals of Geriatric Medicine and Research
Published
2025-05-22
DOI
https://doi.org/10.4235/agmr.24.0191
Primary Topic
Mycobacterium research and diagnosis
Type
article
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article

Community-Acquired Pneumonia with Pseudomonas aeruginosa in a Geriatric Patient with Rheumatoid Arthritis under Baricitinib Treatment

Eva Grundmann, Michael Gagesch, Bertram Feil, S Meier et al.
Annals of Geriatric Medicine and Research
Mycobacterium research and diagnosis
article

Community-Acquired Pneumonia with Pseudomonas aeruginosa in a Geriatric Patient with Rheumatoid Arthritis under Baricitinib Treatment

Eva Grundmann, Michael Gagesch, Bertram Feil, S Meier, Ghazala Gohar
article en

Abstract

Community-acquired pneumonia (CAP) in older patients presents unique diagnostic challenges. Unlike typical presentations with fever and cough, older adults may experience atypical symptoms like falls, confusion, or chronic disease deterioration. Immunomodulatory treatments for autoimmune diseases further complicate infection risks. This is the first case of a severe Pseudomonas aeruginosa pneumonia in an 86-year-old rheumatoid arthritis patient on baricitinib and prednisone. Initially admitted after a fall, she showed no respiratory symptoms but had a chest x-ray revealing extensive infiltrative consolidation. Sputum analysis confirmed the pneumonia, which was successfully treated with antibiotics. Following the resolution of the infection, the immunomodulatory therapy could be safely reintroduced. The case underscores the critical need for comprehensive diagnostic evaluation in older adults on immunomodulatory therapy, emphasizing that subtle, non-respiratory symptoms can mask serious infections and require heightened clinical suspicion.

Annals of Geriatric Medicine and ResearchVol. 29(3)
University of Zurich (CH), Stadtspital Waid (CH)
Good health and well-being
Openalex Percentile: Top 83%
Mycobacterium research and diagnosis
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Community-Acquired Pneumonia with Pseudomonas aeruginosa in a Geriatric Patient with Rheumatoid Arthritis under Baricitinib Treatment — Eva Grundmann, Michael Gagesch, et al. · Annals of Geriatric Medicine and Research (2025) | TGRS Research Map | TGRS