SHengXIaN-QuYu DEcoction in the Treatment of Heart Failure with Reduced and Mildly-Reduced Ejection Fraction (SHINE-HF): rationale and design for a multicenter randomized controlled trial
SHINE-HF will determine the effects of SXQY on patient-reported outcomes (PROs) and symptom burden in patients with HFrEF and HFmrEF. This will shed light on the potential of SXQY as a novel treatment option in improving QoL of patients with HFrEF and HFmrEF.
Authors
- Gui L (ORCID: https://orcid.org/0000-0002-9922-1975)
- Weidong Mao (ORCID: https://orcid.org/0000-0002-9900-8058)
- Sizhen Chen (ORCID: https://orcid.org/0000-0003-2378-4912)
- Jingyi Ren (ORCID: https://orcid.org/0000-0002-9424-4713)
- Chao Zhang (ORCID: https://orcid.org/0000-0002-1172-056X)
- Yonghui Gao (ORCID: https://orcid.org/0000-0002-0311-0083)
- Jiasai Fan
- Jiaying Xu (ORCID: https://orcid.org/0000-0001-9955-6030)
- Lina Feng (ORCID: https://orcid.org/0000-0002-0074-3408)
- Futao Huo
- Meiling Shi
- Li Ding (ORCID: https://orcid.org/0000-0003-1561-0250)
- Ming Wang (ORCID: https://orcid.org/0000-0002-4628-8826)
- Li Shi (ORCID: https://orcid.org/0000-0001-9508-7863)
- Bin Yang (ORCID: https://orcid.org/0000-0003-2467-5320)
- Liyuan Tao (ORCID: https://orcid.org/0000-0003-3497-1326)
- Jianfei Guan
- Xin Li (ORCID: https://orcid.org/0000-0002-4842-5054)
- Fang Fang (ORCID: https://orcid.org/0000-0002-2694-1402)
- Haijun Song
- Xiaobin Wang (ORCID: https://orcid.org/0000-0003-4451-302X)
- Lingling Liu (ORCID: https://orcid.org/0000-0003-0039-7098)
- Hui-Yun Li (ORCID: https://orcid.org/0000-0002-7682-5776)
- Xiaojian Liu (ORCID: https://orcid.org/0000-0002-8884-4448)
- Yan Song (ORCID: https://orcid.org/0000-0003-2049-0214)
- Zhiying Zhang (ORCID: https://orcid.org/0000-0001-6012-0889)
- Hong-Shuai Cao
- Qiao Wang (ORCID: https://orcid.org/0000-0002-8675-5804)
- Xiaohua Zhao (ORCID: https://orcid.org/0000-0003-0838-1090)
- Jiang Liu (ORCID: https://orcid.org/0000-0002-2836-7651)
- Yifei Du (ORCID: https://orcid.org/0000-0002-2262-5808)
- Lingfeng Cao (ORCID: https://orcid.org/0000-0003-0450-7928)
- Hui Xin (ORCID: https://orcid.org/0000-0003-3125-9691)
- Zhiyang Zhu (ORCID: https://orcid.org/0000-0001-9076-7288)
- Jiamei Yang
- Z. Zheng (ORCID: https://orcid.org/0000-0002-4643-6446)
- Lina Su
- Ningsu Kang
- Zai-xiang Shi
- Jin Zhao
- Palidan Wubu'er
Institutions
- Qingdao University (CN)
- Changzhi University (CN)
- Tianjin University of Traditional Chinese Medicine (CN)
- Changzhi Medical College (CN)
- Peking University (CN)
- China-Japan Friendship Hospital (CN)
- Jining Traditional Chinese Medicine Hospital (CN)
- Beijing Chang'an Integrated Traditional Chinese and Western Medicine Hospital (CN)
- Affiliated Hospital of Qingdao University (CN)
- Peking University People's Hospital (CN)
- Zhuhai Hospital of Integrated Traditional Chinese and Western Medicine (CN)
- Xinjiang Uygur Autonomous Region Uygur Medicine Hospital (CN)
- Northern Jiangsu People's Hospital (CN)
- Peking University Third Hospital (CN)
- Urumqi General Hospital of PLA (CN)
- Beijing Hospital of Traditional Chinese Medicine (CN)
- CM Hospital (KR)
- Beijing Fengtai Hospital (CN)
- First Hospital of Qinhuangdao (CN)
- Inner Mongolia Autonomous Region Hospital of Traditional Chinese Medicine (CN)
- Yangzhou University (CN)
Publication Details
- Journal
- Contemporary Clinical Trials Communications
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1016/j.conctc.2025.101497
- Primary Topic
- Cardiovascular Function and Risk Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.00