Prediction of preeclampsia before 11th week of gestation: a secondary analysis of the ASPIRIN trial
This proof-of-concept logistic regression model using first-trimester maternal characteristics demonstrated acceptable predictive performance for preeclampsia/eclampsia before 11.0 weeks of gestation. During this critical period, several interventions could be proposed to reduce preeclampsia risk, including medication adjustments, lifestyle changes, and appropriate referral if needed. Further studies are required to validate these findings and assess their clinical utility in different settings.
Authors
- Mario Rodríguez‐Bosch (ORCID: https://orcid.org/0000-0002-7186-3853)
- Sandra Acevedo‐Gallegos (ORCID: https://orcid.org/0000-0002-8037-2036)
- Y. Copado (ORCID: https://orcid.org/0000-0001-8938-436X)
- M.J. Rodriguez‐Sibaja (ORCID: https://orcid.org/0000-0003-4306-7195)
- Mario I. Lumbreras‐Marquez (ORCID: https://orcid.org/0000-0002-5378-5724)
- Gabriela Capdeville (ORCID: https://orcid.org/0000-0002-1049-3596)
- Yubia Amaya‐Guel
- Andrea Godinez-Medina
Institutions
- Instituto Nacional de Perinatología (MX)
- Centro Médico ABC (MX)
- Universidad Panamericana (MX)
Publication Details
- Journal
- AJOG Global Reports
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1016/j.xagr.2025.100521
- Citations
- 3
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 6.17
Funders
- National Institutes of Health
- National Institute of Child Health and Human Development
- Eunice Kennedy Shriver National Institute of Child Health and Human Development