Protein N-Glycosylation Traits Combined With CA19-9 Accurately Distinguish Pancreatic Cancer Cases From Healthy Controls and Benign Pancreatic Diseases
Both plasma NGTs and CA19-9 distinguish PDAC from a diverse-control cohort. The accuracy further improves when these readouts are combined, showing promise for future early detection methods.
Authors
- Aleksander Bogdański (ORCID: https://orcid.org/0000-0001-8632-9277)
- Yuri E. M. van der Burgt (ORCID: https://orcid.org/0000-0003-0556-5564)
- Michael B. Wallace (ORCID: https://orcid.org/0000-0002-6446-5785)
- Christa M. Cobbaert (ORCID: https://orcid.org/0000-0003-3565-1404)
- Derk C.F. Klatte (ORCID: https://orcid.org/0000-0003-2531-6725)
- Bart E.P.B. Ballieux (ORCID: https://orcid.org/0000-0002-8928-3849)
- Yan Bi (ORCID: https://orcid.org/0000-0001-7427-6219)
- Monique Esther van Leerdam (ORCID: https://orcid.org/0000-0002-5719-3208)
- Manfred Wuhrer (ORCID: https://orcid.org/0000-0002-0814-4995)
- Kristin Clift (ORCID: https://orcid.org/0000-0002-4302-9060)
- Jeanin E. van Hooft (ORCID: https://orcid.org/0000-0002-4424-0079)
- Wilma E. Mesker (ORCID: https://orcid.org/0000-0001-5533-4778)
Institutions
- Leiden University Medical Center (NL)
- Jacksonville College (US)
- WinnMed (US)
- Netherlands Metabolomics Centre (NL)
- Proteogenomics Research Institute for Systems Medicine (US)
- Oncode Institute (NL)
- Mayo Clinic in Florida (US)
Publication Details
- Journal
- Pancreas
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1097/mpa.0000000000002517
- Primary Topic
- Pancreatic and Hepatic Oncology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00