Lab-around-fiber for rapid biological agent detection

Conventional analytical instruments for biochemical detection are costly and complex, driving the need for compact, cost-effective biosensors. These devices integrate molecular recognition elements with detection transducers to link physical, chemical, and biological environments. <br/>LAF (Lab Around Fiber) aims to develop a device for the rapid and simultaneous detection of various biological threats (ricin, botulinum toxin, staphylococcal enterotoxin B, etc.) using optical fibers. This detection is made possible by two main tools: the inscription of fiber Bragg grating (FBG) within the fiber core and the biofunctionalization of the fiber outer silica surface with antibodies specific to the agents to be detected. This device is designed to combine low cost, high sensitivity, multiplexing, and compactness, enabling the biosensor to be used in the field. It is designed to identify the biological threat and quantify it using portable instrumentation.