A Rare Case of Brucellosis With Hepatic Involvement

This case report describes a rare instance of brucellosis with hepatic involvement in a 58-year-old female who contracted the infection after ingesting contaminated dairy products from Mexico. Brucellosis is a zoonotic infection caused by gram-negative coccobacilli of the genus Brucella. The disease is relatively uncommon in the United States due to strict animal health policies; however, it remains a major public health concern in many other countries. Brucellosis typically presents with non-specific symptoms but can rapidly progress to multi-organ involvement. Clinicians should consider brucellosis in patients with non-specific symptoms, particularly those with a history of consuming potentially contaminated products. Diagnosis is typically based on cultures or serology and is subsequently treated with appropriate antibiotic therapy. Here, we present a case of brucellosis that was initially misdiagnosed due to the nonspecific nature of the presenting symptoms, which ultimately led to significant liver involvement. Culture data later confirmed Brucella, and the patient was started on a combination of doxycycline and gentamicin therapy, resulting in the resolution of the disease. This case emphasizes the need for public education on food safety and highlights the risks associated with consuming contaminated products brought into the U.S. from abroad.

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Publication Details

Journal
Cureus
Published
2025-05-22
DOI
https://doi.org/10.7759/cureus.84631
Primary Topic
Brucella: diagnosis, epidemiology, treatment
Type
article
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article

A Rare Case of Brucellosis With Hepatic Involvement

Choung Seng Ly, Muhammad Mansoor Javed, Dillon Drab, F A Abdullah et al.
Cureus
Brucella: diagnosis, epidemiology, treatment
article

A Rare Case of Brucellosis With Hepatic Involvement

Choung Seng Ly, Muhammad Mansoor Javed, Dillon Drab, F A Abdullah, Shivani Desai
article en

Abstract

This case report describes a rare instance of brucellosis with hepatic involvement in a 58-year-old female who contracted the infection after ingesting contaminated dairy products from Mexico. Brucellosis is a zoonotic infection caused by gram-negative coccobacilli of the genus Brucella. The disease is relatively uncommon in the United States due to strict animal health policies; however, it remains a major public health concern in many other countries. Brucellosis typically presents with non-specific symptoms but can rapidly progress to multi-organ involvement. Clinicians should consider brucellosis in patients with non-specific symptoms, particularly those with a history of consuming potentially contaminated products. Diagnosis is typically based on cultures or serology and is subsequently treated with appropriate antibiotic therapy. Here, we present a case of brucellosis that was initially misdiagnosed due to the nonspecific nature of the presenting symptoms, which ultimately led to significant liver involvement. Culture data later confirmed Brucella, and the patient was started on a combination of doxycycline and gentamicin therapy, resulting in the resolution of the disease. This case emphasizes the need for public education on food safety and highlights the risks associated with consuming contaminated products brought into the U.S. from abroad.

CureusVol. 17(5)
Methodist Dallas Medical Center (US)
Good health and well-being
Openalex Percentile: Top 87%
Brucella: diagnosis, epidemiology, treatment
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A Rare Case of Brucellosis With Hepatic Involvement — Choung Seng Ly, Muhammad Mansoor Javed, et al. · Cureus (2025) | TGRS Research Map | TGRS