Metabolomic Profiling of Ocular Fluid Identifies Host Response Factors for Risk Stratification in Bacterial Endophthalmitis
This report is the first of a set of metabolite biomarkers in ocular fluid that correlate with the severity of bacterial endophthalmitis. These biomarkers have the potential to aid in risk stratification and personalized treatment approaches. The metabolomic profiles generated in this study provide insight into the host response mechanisms and the pathophysiology of the infection in human eyes.
Authors
- Vrushali Deshpande (ORCID: https://orcid.org/0000-0001-6758-6091)
- Priyanka Sathe
- Samayitree Das
- Ramaraj Kannan (ORCID: https://orcid.org/0009-0005-9334-8747)
- Padmamalini Mahendradas (ORCID: https://orcid.org/0000-0002-6137-8870)
- Arkasubhra Ghosh (ORCID: https://orcid.org/0000-0002-6570-5891)
- Rohit Shetty
- Naren Shetty
Institutions
- Narayana Nethralaya (IN)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1167/iovs.66.5.27
- Citations
- 1
- Primary Topic
- Ocular Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.71