Ferroptosis Contributes to Retinal Ganglion Cell Loss in GLAST Knockout Mouse Model of Normal Tension Glaucoma
Ferroptosis significantly contributes to RGC and retinal damage in the GLAST-deletion NTG model. Inhibiting ferroptosis with Fer-1 presents a promising therapeutic strategy for protecting visual function in NTG.
Authors
- Shuya Tao
- Wen Hu
- Fan Xu (ORCID: https://orcid.org/0000-0002-1504-2356)
- Huiwen Ye
- Yanlin Feng
- Wu Xiang (ORCID: https://orcid.org/0000-0001-5537-8770)
- Zihao Lin
- Jiawei Wang (ORCID: https://orcid.org/0000-0001-9893-8539)
- Yue Xu (ORCID: https://orcid.org/0000-0002-8065-8253)
- Keyu Liu (ORCID: https://orcid.org/0000-0001-8194-4692)
- Yantao Wei (ORCID: https://orcid.org/0000-0002-0240-2973)
- Qinmeng Shu
- Yue Li (ORCID: https://orcid.org/0009-0006-2228-4771)
- Jingjing Huang (ORCID: https://orcid.org/0000-0002-3009-8681)
Institutions
- Sun Yat-sen University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Fudan University (CN)
- The People's Hospital of Guangxi Zhuang Autonomous Region (CN)
- Science and Technology Commission of Shanghai Municipality (CN)
- Qilu Hospital of Shandong University (CN)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1167/iovs.66.5.26
- Citations
- 8
- Primary Topic
- Glaucoma and retinal disorders
- Type
- article
- Field-Weighted Citation Impact
- 13.66