Cardiac Events in Adults Hospitalized for Respiratory Syncytial Virus vs COVID-19 or Influenza
In this cross-sectional study, 1 in 10 patients hospitalized for RSV had a concurrent acute cardiovascular event. Odds of cardiac events were significantly higher in RSV vs COVID-19 hospitalizations in both vaccine-boosted and unboosted individuals. In contemporaneous hospitalizations for RSV or influenza after the pandemic (2023-2024), odds of heart failure were significantly higher in RSV hospitalizations vs vaccine-breakthrough influenza hospitalizations. These findings suggest that patients with preexisting cardiovascular risk should consider vaccination against RVIs.
Authors
- Calvin J. Chiew (ORCID: https://orcid.org/0000-0002-8217-7971)
- David Chien Lye (ORCID: https://orcid.org/0000-0003-0324-0205)
- Liang En Wee (ORCID: https://orcid.org/0000-0001-6428-9999)
- Jue Tao Lim (ORCID: https://orcid.org/0000-0002-2245-0331)
- Kelvin Bryan Tan
- Rth Ho (ORCID: https://orcid.org/0000-0002-6173-621X)
Institutions
- Ministry of Health (SG)
- National University of Singapore (SG)
- Nanyang Technological University (SG)
- Singapore General Hospital (SG)
- Tan Tock Seng Hospital (SG)
- Duke-NUS Medical School (SG)
- National University Health System (SG)
- National Centre for Infectious Diseases (SG)
Publication Details
- Journal
- JAMA Network Open
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1001/jamanetworkopen.2025.11764
- Citations
- 15
- Primary Topic
- Respiratory viral infections research
- Type
- article
- Field-Weighted Citation Impact
- 20.31
Funders
- Medical Research Council
- National Medical Research Council