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Background: In many developing countries, snakebites still represent a large public health concern.While envenomation may cause substantial morbidity and mortality, the bite itself may pose secondary risks, including infection.Research Questions: What is the prevalence of snakebite infections and what are the bacteria isolated from these infections?Methods: A systematic review of published data was performed using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.Studies were chosen from PubMed (NLM), Scopus (Elsevier), Web of Science (Clarivate), SciELO, and Embase (Elsevier).Studies included cohort, case-control or cross-sectional studies that assessed the prevalence of any of the following: infections in snakebites, the different bacteria identified, or surgical intervention secondary to snakebite infection.There were no exclusions based on age of subjects.All studies included were evaluated for bias using either the Newcastle-Ottawa Scale (NOS) or the adapted NOS.Results: A total of 62 studies (from 525 identified articles) were included (n = 84,296 subjects).These studies were conducted between 1989 and 2022 and on the following continents: Asia (33 studies), the Americas (24 studies), Africa (four studies), and Europe (one study).All studies