Sputum metagenomics in bronchiectasis reveals pan-European variation: an EMBARC-BRIDGE study
Sputum metagenomics confirms and extends prior observations of regional variation in bronchiectasis microbiology. Important variation in the distribution of pathogens and antimicrobial resistance genes has implications for antimicrobial practices across Europe.
Authors
- Fransiskus Xaverius Ivan (ORCID: https://orcid.org/0000-0001-6491-6358)
- Michael R. Loebinger
- Jayanth Kumar Narayana (ORCID: https://orcid.org/0000-0001-8794-9048)
- Josje Altenburg (ORCID: https://orcid.org/0000-0002-7248-963X)
- Michal Shteinberg (ORCID: https://orcid.org/0000-0002-0432-3398)
- Keith Robertson (ORCID: https://orcid.org/0000-0002-6557-8298)
- Oriol Sibila (ORCID: https://orcid.org/0000-0002-4833-6713)
- Charles Haworth (ORCID: https://orcid.org/0000-0001-7126-2874)
- Tavleen Kaur Jaggi (ORCID: https://orcid.org/0000-0003-0097-8853)
- Felix C. Ringshausen (ORCID: https://orcid.org/0000-0001-9084-4968)
- Eva Polverino (ORCID: https://orcid.org/0000-0002-4058-5109)
- Holly Lind
- Daniela Alferes (ORCID: https://orcid.org/0000-0002-5125-1657)
- Katerina Dimakou (ORCID: https://orcid.org/0000-0001-7457-4611)
- Pieter Goeminne (ORCID: https://orcid.org/0000-0001-6220-2220)
- James Duncan Chalmers (ORCID: https://orcid.org/0000-0001-5514-7868)
- Micheál Mac Aogáin (ORCID: https://orcid.org/0000-0002-1726-7700)
- Natalie Lorent (ORCID: https://orcid.org/0000-0002-2653-5885)
- Sanjay H. Chotirmall (ORCID: https://orcid.org/0000-0003-0417-7607)
- Kai Xian Thng
- Amelia Shoemark (ORCID: https://orcid.org/0000-0001-7360-6060)
- Anthony De Soyza (ORCID: https://orcid.org/0000-0002-8566-0344)
- Morven Shuttleworth
- Stefano Aliberti (ORCID: https://orcid.org/0000-0002-0090-4531)
- Pei Yee Tiew
- Jennifer Pollock
- Hollian Richardson
- Merete Bridget Long
Institutions
- Humanitas University (IT)
- Nanyang Technological University (SG)
- Trinity College Dublin (IE)
- Singapore General Hospital (SG)
- Royal Papworth Hospital (GB)
- Freeman Hospital (GB)
- Tan Tock Seng Hospital (SG)
- Ninewells Hospital (GB)
- Amsterdam UMC Location University of Amsterdam (NL)
- Medizinische Hochschule Hannover (DE)
- Royal Brompton Hospital (GB)
- Hospital Clínic de Barcelona (ES)
- Rappaport Family Institute for Research in the Medical Sciences (IL)
- Vlaamse Vereniging voor Obstetrie en Gynaecolo (BE)
- Vall d'Hebron Hospital Universitari (ES)
- German Center for Lung Research (DE)
- St. James's Hospital (IE)
- Sotiria General Hospital (GR)
- Imperial College London (GB)
- KU Leuven (BE)
Publication Details
- Journal
- European Respiratory Journal
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1183/13993003.00054-2025
- Citations
- 8
- Primary Topic
- Cystic Fibrosis Research Advances
- Type
- article
- Field-Weighted Citation Impact
- 12.15
Funders
- Boehringer Ingelheim
- AstraZeneca
- GlaxoSmithKline
- Roche
- Chiesi Farmaceutici
- CSL Behring
- European Respiratory Society
- LifeArc
- Insmed
- National Research Foundation Singapore
- Ministry of Education - Singapore
- Grifols
- National Medical Research Council