Particulate matter-related ITIH4 deficiency is associated with an emphysema phenotype of COPD through JNK-dependent and JNK-independent signalling
We identified a novel pathogenetic mechanism involving ITIH4, where chronic exposure to air pollution induces or promotes emphysema.
Authors
- Shiou‐Fu Lin (ORCID: https://orcid.org/0000-0001-7198-7234)
- Kuan-Yuan Chen (ORCID: https://orcid.org/0000-0002-0266-9627)
- Hsiao‐Chi Chuang (ORCID: https://orcid.org/0000-0003-4651-5192)
- Kang-Yun Lee (ORCID: https://orcid.org/0000-0002-1203-4094)
- Po‐Hao Feng (ORCID: https://orcid.org/0000-0002-3569-3746)
- Yueh-Hsi Chen
- Chien‐Hua Tseng (ORCID: https://orcid.org/0000-0001-7020-1180)
- Tzu-Tao Chen
- Wei-Lun Sun (ORCID: https://orcid.org/0000-0001-7086-4873)
- Chia‐Li Han (ORCID: https://orcid.org/0000-0003-4644-5892)
- Shu‐Chuan Ho (ORCID: https://orcid.org/0000-0002-1616-8647)
- Sheng‐Ming Wu (ORCID: https://orcid.org/0000-0003-1746-5771)
- Cheng‐Wei Lin (ORCID: https://orcid.org/0000-0003-4622-2680)
- Wen-Te Liu
Institutions
- Taipei Medical University-Shuang Ho Hospital (TW)
- Taipei Medical University (TW)
Publication Details
- Journal
- European Respiratory Journal
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1183/13993003.01610-2024
- Citations
- 3
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 4.56
Funders
- National Science and Technology Council
- Taipei Medical University-Shuang Ho Hospital, Ministry of Health and Welfare