Impaired IgA mucosal immunity following lung transplantation: a potential trigger for bronchiolitis obliterans syndrome

This study demonstrates an early impairment of mucosal IgA immunity in LuTx patients, which was linked to the later development of BOS, suggesting that IgA-related markers may serve as early predictors of BOS onset.

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Publication Details

Journal
European Respiratory Journal
Published
2025-05-22
DOI
https://doi.org/10.1183/13993003.02212-2024
Citations
1
Primary Topic
Transplantation: Methods and Outcomes
Type
article
Field-Weighted Citation Impact
2.01

Funders

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article

Impaired IgA mucosal immunity following lung transplantation: a potential trigger for bronchiolitis obliterans syndrome

David Lair, Jérôme Le Pavec, Loïc Falque, Aurélie Daumerie et al.
1 citations
European Respiratory Journal
Transplantation: Methods and Outcomes
2.01
article

Impaired IgA mucosal immunity following lung transplantation: a potential trigger for bronchiolitis obliterans syndrome

David Lair, Jérôme Le Pavec, Loïc Falque, Aurélie Daumerie, Thomas Planté-Bordeneuve, Xavier Demant, Marina Pretolani, Alexandre Vallée, Olivier Brugière, Jean‐François Mornex, Nicolas Heddebaut, François Michel Carlier, Vincent Bunel, Charles Pilette, Adrien Tissot, Sandrine Hirschi, Élisabeth Longchampt, Jérôme Ambroise, M. Reynaud-Gaubert, Bruno Detry
article en
1 citations

Abstract

This study demonstrates an early impairment of mucosal IgA immunity in LuTx patients, which was linked to the later development of BOS, suggesting that IgA-related markers may serve as early predictors of BOS onset.

European Respiratory JournalVol. 66(5)
Université Claude Bernard Lyon 1 (FR), Délégation Paris 5 (FR), Cliniques Universitaires Saint-Luc (BE), Inserm (FR), École Pratique des Hautes Études (FR), Lyon College (US), Université Paris Cité (FR), Centre Hospitalier Universitaire de Grenoble (FR), Centre Hospitalier Universitaire de Bordeaux (FR), Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement (FR), CHU Dinant Godinne UCL Namur (BE), Assistance Publique – Hôpitaux de Paris (FR), Hospices Civils de Lyon (FR), Centre Chirurgical Marie Lannelongue (FR), Hôpital Nord (FR), Institut du Thorax (FR), Hôpital Bichat-Claude-Bernard (FR), Hôpitaux Universitaires de Strasbourg (FR), Hôpital Foch (FR), Directorate-General Joint Research Centre (BE), UCLouvain (BE)
Association Vaincre la Mucoviscidose
Good health and well-being
Openalex Percentile: Top 15%
Transplantation: Methods and Outcomes
2.01
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