Anticoagulation Timing in Acute Stroke With Atrial Fibrillation According to Chronic Kidney Disease: The OPTIMAS Trial
Authors
- László Sztriha (ORCID: https://orcid.org/0000-0002-8698-6514)
- Giles Thomas (ORCID: https://orcid.org/0000-0002-6122-4329)
- Tamara Hughes
- Amalia Ndoutoumou (ORCID: https://orcid.org/0000-0002-0982-1222)
- Rushika Saksena (ORCID: https://orcid.org/0000-0002-0101-9569)
- Robert Gibson
- Melroy A. D’Souza (ORCID: https://orcid.org/0000-0002-6798-8960)
- Peter Wanklyn
- Martin Cooper (ORCID: https://orcid.org/0000-0003-4853-053X)
- Jason Kho (ORCID: https://orcid.org/0000-0003-3377-4750)
- Kamy Thavanesan
- David Hervás (ORCID: https://orcid.org/0000-0003-0635-4961)
- Laura Yates (ORCID: https://orcid.org/0000-0002-7963-625X)
- Sheila Mashate
- Susan A. McDonald
- Saji Philip (ORCID: https://orcid.org/0000-0001-8551-8420)
- Gyöngyi Szabó (ORCID: https://orcid.org/0000-0003-0836-2527)
- Robert Fenner (ORCID: https://orcid.org/0000-0002-5819-9601)
- Wayne Old (ORCID: https://orcid.org/0000-0003-2120-7599)
- Manju Krishnan (ORCID: https://orcid.org/0009-0000-8581-5679)
- S.M. Arif (ORCID: https://orcid.org/0000-0002-2917-3226)
- T Anton Margaret
- Ankita Misra (ORCID: https://orcid.org/0000-0001-6794-9657)
- Aneet Gill (ORCID: https://orcid.org/0009-0005-9248-8406)
- Ruwan Parakramawansha
- E. Spruce
- Krešo Jergović
- Kevin Dunne (ORCID: https://orcid.org/0009-0003-0393-8037)
- AK Annamalai
- Colin H. Macphee
- Saul Sundayi
- Amit K Kishore (ORCID: https://orcid.org/0000-0003-1820-8697)
- Fredie Robinson (ORCID: https://orcid.org/0000-0001-6844-5063)
- Shoba Abraham
- Daniel Esteban (ORCID: https://orcid.org/0000-0001-8897-3170)
- Angela Foulds
- Naweed Sattar
- Madana Meegada
- Sabri Soussi (ORCID: https://orcid.org/0000-0002-1489-4768)
- Neelima Mannava
- Tal Anjum
- M. Gabrielle Pagé (ORCID: https://orcid.org/0000-0002-7742-2717)
- Timothy J. England (ORCID: https://orcid.org/0000-0001-5330-8584)
- Aline da Rocha Matos (ORCID: https://orcid.org/0000-0001-7763-2127)
- Emelda Veraque
- D. Fellowes
- Michelle Davis (ORCID: https://orcid.org/0000-0001-8876-9188)
- Fergus Doubal (ORCID: https://orcid.org/0000-0002-2769-3148)
- Samer Al‐Hussayni
- Tracy Marsden
- Katja Adie
- Claire Pegg
- Irmak Salt (ORCID: https://orcid.org/0000-0003-0697-7085)
- Eleanor Williams (ORCID: https://orcid.org/0000-0002-0851-7990)
- Sissi Ispoglou
- Nigel Temple (ORCID: https://orcid.org/0000-0003-1907-3894)
- Tim Harris (ORCID: https://orcid.org/0000-0001-9628-130X)
- Kathryn Cawley
- Seema Alam (ORCID: https://orcid.org/0000-0003-0888-8625)
- Syed Masudur Rahman Dewan (ORCID: https://orcid.org/0000-0003-1443-7150)
- Mark White (ORCID: https://orcid.org/0000-0002-6309-3254)
- Ben Sanders (ORCID: https://orcid.org/0000-0002-5629-8593)
- Kausik Chatterjee (ORCID: https://orcid.org/0000-0002-3093-1469)
- Michael McCormick
- Paul Bradley (ORCID: https://orcid.org/0000-0002-4060-9932)
- Puneet Kakar
- Emma Levell
- Vera Cvoro (ORCID: https://orcid.org/0000-0002-3913-5100)
- Charlotte Kamundi
- J. Beavan
- Joe Devine (ORCID: https://orcid.org/0000-0002-9658-6733)
- Louise Cabrelli
- Rachel Evans (ORCID: https://orcid.org/0000-0003-0960-9843)
- Bindu Gregary (ORCID: https://orcid.org/0000-0002-6825-6753)
- Kim W. Carter (ORCID: https://orcid.org/0000-0002-4904-2872)
- Mohit Bhandari (ORCID: https://orcid.org/0000-0003-3556-9179)
- Luke Bridge
- Nasarudin Ahmad (ORCID: https://orcid.org/0000-0002-2841-1958)
- C. Padilla-Harris
- Gianna Wilkie (ORCID: https://orcid.org/0000-0002-1712-0514)
- Alison Hayes (ORCID: https://orcid.org/0000-0002-8679-6040)
- Emilia Caverly (ORCID: https://orcid.org/0000-0002-4420-713X)
- Pauline Slade (ORCID: https://orcid.org/0000-0001-5877-2706)
- Tracey Taylor (ORCID: https://orcid.org/0000-0002-2742-7544)
- Helen Maguire (ORCID: https://orcid.org/0000-0001-5743-6188)
- Neil Oakley (ORCID: https://orcid.org/0000-0003-4917-3669)
- Simon Beddows (ORCID: https://orcid.org/0000-0002-6879-6215)
- Nazima Nisar
- Kathleen Courtney
- Sean Bell (ORCID: https://orcid.org/0000-0003-4730-9438)
- Sharon Tysoe
- Allan MacRaild (ORCID: https://orcid.org/0000-0002-2000-1460)
- Richard Marigold (ORCID: https://orcid.org/0000-0003-1924-1616)
- S. Saxena (ORCID: https://orcid.org/0000-0003-3511-9303)
- Praveen Sridhar (ORCID: https://orcid.org/0000-0002-9622-8063)
- Wageeh Hassan Sayed
- Bernard Esisi
- Julie Fox (ORCID: https://orcid.org/0000-0002-0583-8019)
- M. Khaddour
- Kerry M. Smith
- Rachel Teal
- Derek Esson
- Abhinav Singh (ORCID: https://orcid.org/0000-0002-7329-6792)
- Raymond B. Penn (ORCID: https://orcid.org/0000-0001-8452-5880)
- Archana Jayanthi
- Andrea Warwick (ORCID: https://orcid.org/0000-0003-3937-5638)
- Camilla Russo (ORCID: https://orcid.org/0000-0002-2256-7281)
- Jennifer A. M. Philip (ORCID: https://orcid.org/0000-0002-3312-0645)
- A. O’Kelly
- Sharon Dealing
- John T. Benjamin (ORCID: https://orcid.org/0000-0002-0930-1753)
- Sharon Keenan
- Salman Khan (ORCID: https://orcid.org/0000-0001-8003-6983)
- James Teo (ORCID: https://orcid.org/0000-0002-6899-8319)
- Edward Littleton
- Steven L. Sayers (ORCID: https://orcid.org/0000-0003-3710-9926)
- Hedley Emsley (ORCID: https://orcid.org/0000-0003-0129-4488)
- E. Tone
- Mitali Kini (ORCID: https://orcid.org/0000-0003-2689-6231)
- Helen Tench
- M. Slaughter (ORCID: https://orcid.org/0009-0007-1565-0806)
- Louise Mallon
- Thomas F. Fuller (ORCID: https://orcid.org/0000-0001-5474-2876)
- Peter Anderton
- E Hindley
- Kyung-hwan Kong
- Nick Freemantle (ORCID: https://orcid.org/0000-0001-5807-5740)
- Mónica Recamán
- Duyen Ngo (ORCID: https://orcid.org/0000-0001-6125-7756)
- Mandy Couser
- Sabine Maguire (ORCID: https://orcid.org/0000-0001-9870-0547)
- Liz Shepherd
- Sarah L. Whitehouse (ORCID: https://orcid.org/0000-0002-3260-4736)
- David O. Cosgrove
- J Selwyn
- Mark Barber (ORCID: https://orcid.org/0000-0002-2893-1566)
- Keren Northcott
- Niall A. Smyth (ORCID: https://orcid.org/0000-0002-4527-9637)
- William Longley
- Christian Hacon
- Alan Neal
- Caroline J Doré
- Vaikuntam Srinivasan
- Sara Mazzucco (ORCID: https://orcid.org/0000-0002-1582-6724)
- Aditya Nair (ORCID: https://orcid.org/0000-0003-4218-4154)
- Brian Reed (ORCID: https://orcid.org/0000-0002-1078-9215)
- Liz Arram
- Sinoj Antony (ORCID: https://orcid.org/0000-0001-5500-375X)
- Muhammad Farman (ORCID: https://orcid.org/0000-0001-7616-0500)
- Arunodaya R. Gujjar (ORCID: https://orcid.org/0000-0003-1692-5238)
- Khaled Rashed (ORCID: https://orcid.org/0000-0003-0476-9098)
- Margot J. Davey
- Gregory Y.H. Lip (ORCID: https://orcid.org/0000-0002-7566-1626)
- Simon Finch
- Yousif Behnam
- Vanessa Rivers
- Paula Harman
- Memory Mwadeyi
- S. Sreedevi Raj
- I. Ponce (ORCID: https://orcid.org/0000-0001-5020-3736)
- Marie Evans (ORCID: https://orcid.org/0000-0001-8650-5795)
- Lukuman Gbadamoshi
- Peter Ferdinand (ORCID: https://orcid.org/0000-0001-6834-6428)
- O Quinn
- Navraj Chattha
- D Catibog
- Elaine Siddle
- Deborah Ward (ORCID: https://orcid.org/0000-0002-3603-964X)
- D. Eveson
- Gearóid Crosbie
- Eric Q. Colquhoun
- Lisa G. Wood (ORCID: https://orcid.org/0000-0002-0941-9225)
- James Choulerton
- Anthony Kenton
- Maryam Balogun (ORCID: https://orcid.org/0009-0006-8006-0522)
- M.R. Chowdhury
- Ahmed Naqvi (ORCID: https://orcid.org/0000-0002-9645-5856)
- Mohammad Al Hasan (ORCID: https://orcid.org/0000-0002-8279-1023)
- Shannon Frank
- Emma E. Wilson (ORCID: https://orcid.org/0000-0002-4695-2184)
- Jesmin Antony (ORCID: https://orcid.org/0000-0002-4101-8616)
- Jack Galliford
- A. Asaipillai
- Mariana Castanheira (ORCID: https://orcid.org/0000-0003-0126-1782)
- Emma Clarkson
- C Fornolles
- Min Myint
- Ramesh Bhat Y (ORCID: https://orcid.org/0000-0003-2919-6361)
- Hilary Wyllie
- A. Bradley (ORCID: https://orcid.org/0009-0003-4482-0748)
- J.R. Owen
- Jerrin Thomas (ORCID: https://orcid.org/0000-0002-3788-4378)
- Heather McGuinness
- Lynne Reid (ORCID: https://orcid.org/0000-0002-5507-1768)
- AMY SANGHAVI SHAH (ORCID: https://orcid.org/0000-0001-7297-139X)
- Benjamin Richard (ORCID: https://orcid.org/0000-0003-4531-1905)
- Syed Ali Raza (ORCID: https://orcid.org/0000-0003-4782-2100)
- Travis T. Sims (ORCID: https://orcid.org/0000-0003-1975-0795)
- A. Ekkert
- Rania Francis
- D Arcoria
- Zachary D. Horne (ORCID: https://orcid.org/0000-0002-7668-6200)
- Janice Irvine
- Neshika Samarasekera (ORCID: https://orcid.org/0000-0001-6840-0199)
- G. Crossingham
- Jo Howe (ORCID: https://orcid.org/0000-0002-7567-075X)
- Ramanathan Kirthivasan
- S. Sakthivel
- Youssif Abousleiman
- Kate Bennett (ORCID: https://orcid.org/0000-0002-2358-4497)
- Brendan Affley
- Naval Shinh
- Brian Clarke (ORCID: https://orcid.org/0000-0003-3772-2202)
- Elisa Porretta
- Zain Mehdi (ORCID: https://orcid.org/0000-0001-8251-4205)
- Vivek Pravin Dave (ORCID: https://orcid.org/0000-0003-2589-666X)
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- J. Mitchell-Douglas
- S Duberley
- L. Broad (ORCID: https://orcid.org/0009-0006-0754-4547)
- Paul Guyler
- David R. Hargroves (ORCID: https://orcid.org/0000-0003-0127-3011)
- Inez Wynter
- R. Price
- E.C.J.H. Phiri
- Jorgé Reyes (ORCID: https://orcid.org/0000-0003-3065-8674)
- A. Kostyuk (ORCID: https://orcid.org/0000-0001-6538-1324)
- Esther Erumere
- Susovan Banerjee (ORCID: https://orcid.org/0000-0001-7029-9464)
- Philip S. Nash (ORCID: https://orcid.org/0000-0003-2428-1575)
- Nikola Sprigg (ORCID: https://orcid.org/0000-0002-5871-8168)
- Ruth Bellfield
- Waheed Murad (ORCID: https://orcid.org/0000-0002-2551-9998)
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- Rachael Hunter (ORCID: https://orcid.org/0000-0002-7447-8934)
- Aleksandra Hedström (ORCID: https://orcid.org/0000-0003-0452-3610)
- Hasan Erdoğan (ORCID: https://orcid.org/0000-0001-5141-5108)
- German Guzman-Gutierrez
- Robert Tempest (ORCID: https://orcid.org/0000-0001-7635-7442)
- Diana G. Beeby
- M. New
- Jahanzeb Rehan
- Alpha Anthony
- Raj Bathula (ORCID: https://orcid.org/0000-0003-4550-8943)
- K. Musarrat
- E. Baker
- Macey L. Murray (ORCID: https://orcid.org/0000-0001-6418-0854)
- Yee‐Haur Mah
- Lakshmanan Sekaran (ORCID: https://orcid.org/0009-0005-8037-6917)
- Gareth Blayney
- Stefan T. Engelter (ORCID: https://orcid.org/0000-0003-3855-6234)
- Gary A. Ford (ORCID: https://orcid.org/0000-0001-8719-4968)
- D. McFarland
- Assunção Tuna (ORCID: https://orcid.org/0000-0002-6582-7477)
- C. C. Belo (ORCID: https://orcid.org/0000-0002-6046-5585)
- A. Shetty (ORCID: https://orcid.org/0000-0001-6752-718X)
- Jesse Dawson (ORCID: https://orcid.org/0000-0001-7532-2475)
- Jennifer Scott (ORCID: https://orcid.org/0000-0001-8837-5250)
- Mitchell J. Magee
- Wai Meng Yu
- Ammad Mahmood (ORCID: https://orcid.org/0000-0001-5138-6706)
- R. Varquez
- Kate Leslie Harkness (ORCID: https://orcid.org/0000-0002-0319-8994)
- Bo Norrving (ORCID: https://orcid.org/0000-0002-8024-5096)
- Evelyn Nadar
- Rita Dhami
- G. Fletcher
- Helen Sutherland
- Cornelius James Fernandez (ORCID: https://orcid.org/0000-0002-1171-5525)
- Telma Costa (ORCID: https://orcid.org/0000-0002-9625-1124)
- Michelle M. Nash (ORCID: https://orcid.org/0000-0002-9940-9214)
- Andrew John Davies (ORCID: https://orcid.org/0000-0002-7517-6938)
- David Collins. Wheeler (ORCID: https://orcid.org/0000-0003-0745-3478)
- Sanjeev Kumar (ORCID: https://orcid.org/0000-0002-8115-353X)
- Iqbal Anwar (ORCID: https://orcid.org/0000-0003-4822-214X)
- Adrian Brown (ORCID: https://orcid.org/0000-0003-1818-6192)
- Nabeel Khan (ORCID: https://orcid.org/0000-0002-5368-7518)
- Kiruba Nagaratnam (ORCID: https://orcid.org/0000-0003-1455-2773)
- Carolyn Gabriel
- Norin Ahmed (ORCID: https://orcid.org/0000-0001-8798-5217)
- Hannah Cohen (ORCID: https://orcid.org/0000-0003-2032-390X)
- Lucy Knibbs
- S. Shekar
- Harald Proeschel
- Imran Ashraf (ORCID: https://orcid.org/0000-0002-8271-6496)
- Sharon Storton
- Jonathan G. Best (ORCID: https://orcid.org/0000-0002-4243-5753)
- Adrian Byrne (ORCID: https://orcid.org/0000-0003-4887-2572)
- E. Cruddas
- Suzanne Ragab
- S. Hunte
- D. Dutta
- Becky Icke
- J. Ribamar Costa (ORCID: https://orcid.org/0000-0001-6286-3109)
- Christianne Micallef (ORCID: https://orcid.org/0000-0002-4513-8199)
- M. Bajoriene
- Cosmas Anazodo
- Alfonso Tanate
- Richard Pugh (ORCID: https://orcid.org/0000-0002-2848-4444)
- Victor L. Slater
- D Maren
- Krystina B. Lewis (ORCID: https://orcid.org/0000-0001-6761-7548)
- Luke Dixon (ORCID: https://orcid.org/0000-0003-4060-7897)
- B. Sari (ORCID: https://orcid.org/0009-0001-2395-8751)
- Shakeel Ahmad (ORCID: https://orcid.org/0000-0001-6651-9399)
- N. Singh (ORCID: https://orcid.org/0000-0002-3690-2327)
- Hakim‐Moulay Dehbi (ORCID: https://orcid.org/0000-0002-0816-0178)
- K. Hubbard
- Tarak Patel
- H. Hughes (ORCID: https://orcid.org/0000-0002-1069-9922)
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- Jacob H. Rand (ORCID: https://orcid.org/0000-0003-4084-6820)
- H. Chandrashekar
- Anne Baird
- D. Sims
- Lauren Binnie
- James McIlmoyle
- Linetty Makawa
- J Finch
- Frances Justin
- Neal Mehta (ORCID: https://orcid.org/0000-0001-8185-4478)
- Tishok Vanniyasingam
- Kàren Morgan (ORCID: https://orcid.org/0000-0001-6193-1747)
- Emma Richards (ORCID: https://orcid.org/0000-0001-6691-2377)
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- John C. Kirkham
- Naveen Gadapa
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- Martin James (ORCID: https://orcid.org/0000-0001-6065-6018)
- S. Kausar
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- Deborah Walstow
- Laman A. Gray
- JAA Borland
- Louise Shaw (ORCID: https://orcid.org/0000-0003-2973-756X)
- David John Werring (ORCID: https://orcid.org/0000-0003-2074-1861)
- Sudhir Tauro (ORCID: https://orcid.org/0000-0002-7236-970X)
- Kerstin Metcalf
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- Ronda Loosley
- Brian Menezes (ORCID: https://orcid.org/0000-0003-1053-0788)
- Dogan Abdullah
- Aricsa Mariya Joshy
- E Kinsella-Perks
- Tomas Hannam-Penfold
- Sarah Risbridger (ORCID: https://orcid.org/0000-0001-8186-6989)
- Gita Gramizadeh
- V. Nelatur
- Samantha Bayhonan
- Victoria Mead
- Liqun Zhang (ORCID: https://orcid.org/0000-0002-2103-6294)
- Albert V. Smith (ORCID: https://orcid.org/0000-0003-1942-5845)
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- Siow Teng Chan
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- Raj Shekhar (ORCID: https://orcid.org/0000-0001-5799-0736)
- Tim Harrison
- Vanessa Moore (ORCID: https://orcid.org/0009-0009-5453-540X)
- S. Natarajan
- M.J. Macleod
- Cheul-Muu Sim
- S. Choudhary
- Hassan
- Afzal Azim
- J. C. Williams
- Victoria Riddell
- CDR I Kamara
- E. Jamieson
- Hannah Sims
- Mairead Cullen
- Mark Willmot
- Luiz Antonio Oliveira Inácio
- P G Gopi
- Dumin Karunatilake
- Paul Fearon
- Jeffery Joseph
- Saidu B. Abubakar
- F O Omoregie
- A C Cave
- Catherine Curley
- M. Fawcett
- C. Fernández Aguirre
- Emma Parker
- Bhupinder Sandhu
- G. Tallon
- R Wolf-Roberts
- Gary R. Marshall
- Toby Black
- C. A. Parker
- Johanne Dubé
- Sandeep Buddha
- Lisa Parfitt
- A. Dixit
- J. Perez
- John Gardner
- J Phipps
- Cynthia Patterson
- S Leason
- L O'Brien
- S. Hewson
- Lisa R. King
- Mark Garside
- John C. France
- L. Griebel
- S. Lee
- A. Bakshi
- Anne Morgan
- S. Board
- Laura McCafferty
- S. Ankolekar
- A. A. Lyle
- S. Sultan
- C. Burt
- G Hector
- H. Bains
- Brown J. Okoko
- Jan Angus
- L. Blasco
- A Bowring
- V Johnson
- Thin M Soe
- S Coetzee
- W. Goddard
- Agrawal Deepa Manoj
- Sue Massingham
- Iwona Mazurczak
- Coleen Ditchfield
- Sam King (ORCID: https://orcid.org/0000-0002-4414-6015)
- Grace Fawehinmi (ORCID: https://orcid.org/0009-0006-1027-0444)
- L. Poolon
- S. Mariampillai
- M. Tibajai
- C. Sheriden
- S. Luxmore-Brown
- E. Anyankpele
- F. Al Shalchi
- S. Heirons
- H. Stoney
- K. Serac
- K. Gillmain
- T. Hallows
- O. Ebueka
- L. Moram
- S. Mavinamne
- J. Kresmir
- I. Wijenayake
- M. Badanahatti
- M. Karwacka-Cichomska
- B. Kariyadil
- L. Vonoven
- J. Mabutti
- P. Patiola
- D. Keely
- C. Ambrico
- P. Wilcoxson
Institutions
- University College Hospital (GB)
- University of Liverpool (GB)
- King's College London (GB)
- Royal Devon and Exeter Hospital (GB)
- Royal London Hospital (GB)
- University of Oxford (GB)
- Liverpool Heart and Chest Hospital (GB)
- MRC Clinical Trials Unit at UCL (GB)
- Institute of Mental Health (GB)
- Felix Platter-Hospital (CH)
- Anna Needs Neuroblastoma Answers (US)
- Skåne University Hospital (SE)
- Comprehensive Clinical Trials (US)
- University College London (GB)
- Aalborg University (DK)
Publication Details
- Journal
- Stroke
- Published
- 2025-05-22
- DOI
- https://doi.org/10.1161/strokeaha.125.051457
- Citations
- 2
- Primary Topic
- Atrial Fibrillation Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 2.78
Funders
- Amgen
- Pfizer
- AstraZeneca
- GlaxoSmithKline
- Sanofi
- Gilead Sciences
- Alexion Pharmaceuticals
- Alnylam Pharmaceuticals
- Queen Mary University of London
- Vertex Pharmaceuticals
- Aimmune Therapeutics
- Argenx
- National Institute for Health and Care Research
- University of Oxford
- Gedeon Richter
- Novo Nordisk
- Astellas Pharma
- Fondazione Internazionale Menarini
- Galderma
- Ipsen
- Janssen Biotech
- Daiichi Sankyo Europe